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Cellular therapy, Chicago

Cellular therapy is an innovative treatment that’s helping a growing number of patients. At City of Hope® Cancer Center Chicago, our Cellular Therapy Program offers leading options—including chimeric antigen receptor (CAR) T-cell therapy and tumor-infiltrating lymphocyte (TIL) therapy—for qualifying patients in the Midwest.

Chicago cell therapy, the City of Hope way

At our Chicago Cellular Therapy Program, you’ll find experts with deep experience using CAR T-cell and TIL therapies to treat chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), non-Hodgkin’s lymphoma and multiple myeloma. Collecting your cells and re-infusing them happens all under one roof —so your care is seamless. We also offer clinical trials, giving patients access to the newest CAR T-cell therapy options.

While CAR T-cell therapy and TIL therapy have brought new hope to many patients, they also have the potential to cause serious side effects. That’s why our care team monitors patients closely throughout treatment and is ready to treat side effects that may arise.

Call now to schedule your appointment at City of Hope Chicago

  • A team of highly trained, multidisciplinary experts dedicated to curing cancer
  • Leading-edge diagnostic and treatment tools and technologies 
  • A personal patient concierge to gather your records, help schedule appointments and answer your questions, in real time
  • Integrative care to help manage side effects and maintain your quality of life
  • Assistance coordinating transportation and travel for appropriate patients*
*If you’re a beneficiary of a government health insurance program, such as Medicare or Medicaid, City of Hope is not permitted to provide travel, lodging or transportation benefits.

Your Chicagoland CAR T-cell therapy experts

CAR T-cell therapy, or chimeric antigen receptor T-cell therapy, is a leading-edge treatment that uses your own immune system to fight cancer. Your T-cells are collected, reprogrammed in the lab to recognize cancer cells, then returned to your body to attack the disease.

At City of Hope Chicago, we understand that specialized care matters. That’s why you can count on a care team with extensive experience in CAR T-cell therapy for chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), non-Hodgkin’s lymphoma and multiple myeloma. Every step of your care is performed onsite for your safety, comfort and convenience.

TIL therapy for patients across the Midwest

Tumor-infiltrating lymphocyte (TIL) therapy is an emerging treatment that uses your body’s own immune cells to fight disease. TILs are a special kind of white blood cell found inside tumors. During treatment, these cells are collected through surgery, multiplied and “supercharged” in the lab, then returned to your body to help attack the cancer.

Before your TILs are given back, you’ll receive a short course of chemotherapy  to prepare your immune system so the treatment can work more effectively.

TIL therapy, currently approved by the U.S. Food and Drug Administration for certain patients with advanced melanoma, is showing promise as an option earlier in treatment.

As a patient at City of Hope Chicago, you benefit from a highly specialized team that may include medical oncologists, surgical oncologists and experts in cellular therapy, hematology, transplant and immunotherapy. You’ll also be supported by specially trained oncology nurses and care coordinators who guide you through each step of the TIL therapy journey.

City of Hope Chicago’s cell therapy expertise

When it comes to cellular therapy in the Midwest, you’ll find expertise, innovation and compassionate care—all close to home at our comprehensive cancer center in Lake County, Illinois.

At a Glance: The City of Hope Chicago Difference

  • Convenient location midway between Chicago and Milwaukee, with affordable on-site lodging so your loved ones can stay nearby during treatment
  • Nationally recognized quality and safety, including:
    • FACT accreditation — the gold standard for cellular therapy excellence
    • A “high performing” rating in leukemia, lymphoma and multiple myeloma treatment by U.S. News & World Report (2025–26)
    • Magnet® recognition for nursing excellence—achieved by fewer than 10 percent of hospitals nationwide
    • 5-star overall and patient experience ratings from the Centers for Medicare & Medicaid Services (CMS)
    • CAP accreditation for our lab, which meets strict standards for tissue collection, preparation and testing
    • Association for the Advancement of Blood & Biotherapies (AABB) accreditation for the highest standards in blood banking and transfusion services
  • Access to clinical trials, including CAR T-cell studies and a new trial for multiple myeloma
  • Supportive care, like behavioral health therapy and nutrition support, to address physical and emotional side effects
  • Survivorship support, with individualized follow-up care for blood cancer patients
Foundation for the Accreditation of Cellular Therapy logo

Chicago

Cancer Center

2520 Elisha Avenue
Zion, Illinois 60099