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Non-Hodgkin lymphoma

The information on this page was reviewed and approved by
Maurie Markman, MD, President, Medicine & Science at CTCA.

This page was updated on July 14, 2021.

Non-Hodgkin lymphoma is a complicated disease. Our oncologists are here to help.

Non-Hodgkin lymphoma is the most common form of blood cancer, or liquid cancer. The disease forms in the bloodstream or lymph system, a network of vessels, nodes and organs that carry immune cells throughout the body. More than 70,000 cases of non-Hodgkin lymphoma are diagnosed each year and include dozens of types and sub-types. The disease is similar in some ways to Hodgkin lymphoma and leukemia, but these cancers also differ in important ways. Most forms of non-Hodgkin lymphoma develop when immune cells mutate or become damaged and begin to grow out of control, crowding out healthy immune cells. These cells may also form tumors in the lymph nodes, spleen and other organs.

Considering its complexities and the serious nature of this disease, it is important to consult with an experienced team of cancer doctors and clinicians trained to identify each patient’s specific cancer type and develop a treatment plan tailored to the individual needs involved. At Cancer Treatment Centers of America® (CTCA), our medical oncologists, hematologist-oncologists and other experts have years of experience delivering the standard-of-care and precision cancer treatments available to treat non-Hodgkin lymphoma. Our whole-person care model is also designed to support patients throughout the treatment journey, offering supportive care services to help them manage side effects and maintain their quality of life.

What you should know after a non-Hodgkin lymphoma diagnosis

Treatment options

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Treatment for non-Hodgkin lymphoma generally depends on the type and stage of the cancer, as well as treatment goals. For example, some palliative treatments may be beneficial in helping patients prevent or treat non-Hodgkin lymphoma-related side effects, such as infections and low blood cell counts. Treatments for non-Hodgkin lymphoma may include:

Chemotherapy may be prescribed to treat all types of non-Hodgkin lymphoma, and to prevent the disease from recurring.

Radiation therapy
Radiation therapy may be used to treat non-Hodgkin lymphoma, and/or relieve pain and discomfort caused by an enlarged spleen or swollen lymph nodes.

Stem cell transplantation
A stem cell transplant, which infuses healthy blood-forming stem cells into the body, may be an option for some patients.

Targeted therapy
Targeted therapy drugs that use immune cells engineered in a laboratory to target lymphoma cells may be recommended.

Learn more about treatments for non-Hodgkin lymphoma

Supportive care

Non-Hodgkin lymphoma and its treatment may cause stress on your musculoskeletal system, as well as aches and pains in your neck and/or back, headaches and difficulty walking. The disease also may affect physical functioning and energy, and patients who have received a stem cell transplant may experience a lower white blood cell count, increasing the risk of infection.

Supportive care clinicians work to help non-Hodgkin lymphoma patients manage the side effects caused by their disease or its treatment. These therapies may include:


​Oncology rehabilitation

​Oncology rehabilitation includes a wide range of therapies designed to help you build strength and endurance.


​Nutritional support

Every patient has the option of meeting with a registered dietitian.


Behavioral health

​Our behavioral health support program is designed to support you and your caregivers before, during and after cancer treatment.

Randy Knight

Randy K.

Non-Hodgkin Lymphoma

"People at CTCA are enthusiastic and they care. It's all over their faces and in their body language. It's very easy to embrace an organization that offers hope to people in a very real and genuine way. It’s inspired me. I feel blessed to be able to speak to others and give them hope, and do so in a heartfelt way."


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