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Ajaz M. Khan,

M.D., M.B.A., C.P.E.

Chief of Medical Oncology and President, Medical Staff for Chicago

4.9 (176 Ratings)
Biography photo
My desire is to provide the best possible care by focusing on developing long-term relationships with my patients and their families so they can truly understand their goals, concerns and needs. The ability to provide high-quality, patient-centered, and personalized care deeply attracted me to City of Hope.
Location
City of Hope Chicago
2520 Elisha Ave.
Zion, IL 60099
City of Hope Downtown Chicago
160 Upper E. Illinois St.
Chicago, IL 60611
Specialties
Medical Oncology
Breast Oncology
Gastrointestinal Cancer
Head and Neck Oncology
Thoracic Oncology
Hematologic Oncology
Education
Medical school:

St. George's University School of Medicine, Grenada, West Indies

Residency:

Internal Medicine - Drexel University, College of Medicine, Philadelphia, PA

Fellowship:

Hematology and Medical Oncology - Newark Beth Israel Medical Center, Newark, NJ

Advanced degrees:

Master of Business Administration - George Washington University School of Business, Washington, D.C.

Academic Appointments
  • Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research
Certifications

Internal Medicine, Hematology and Medical Oncology – American Board of Internal Medicine

About Me

Dr. Ajaz M. Khan joined City of Hope® Chicago in March 2022 as a Medical Oncologist. In his leadership role as Chief of Medical Oncology, Dr. Khan is responsible for guiding protocols, ensuring standard-of-care guidelines are consistently met and exceeded, and helping recruit high-quality physicians to City of Hope. In 2025, he was elected as the President of the Chicago Medical Staff. As a Medical Oncologist, Dr. Khan primarily focuses on treating patients with breast, lung, and gastrointestinal cancers.

“My goal with my patients is to provide education, compassionate care and open lines of communication,” says Dr. Khan, “and to bring information and treatment options to them, communicating clearly, so they have a comprehensive understanding of the possible next steps forward.” Dr. Khan also strives to form relationships with his patients, making sure he is easily reachable, so they can get in touch when they need him.

After his mom died from cancer when he was five years old, Dr. Khan questioned why cancer had taken her from him and what could be done to improve the lives of patients and their families. This life-long interest led him to become a research assistant during his undergraduate years, and later to serve as an Associate Scientist in Research and Development at Bayer Corporation. During this time, Dr. Khan was influenced by the oncologists he worked with, furthering his interest in treating cancer and inspiring his decision to become a medical oncologist.

After earning his medical degree with honors from St. George's University School of Medicine in Grenada, West Indies, Dr. Khan completed his residency in Internal Medicine at Drexel University School of Medicine in Philadelphia, Pennsylvania. He went on to complete a fellowship in hematology and medical oncology at Newark Beth Israel Medical Center in Newark, New Jersey, where he became Chief Fellow, ASCO Merit Award Recipient and MORE Foundation Scholar. Dr. Khan received his MBA from George Washington University School of Business in Washington, D.C., with top honors.

Before coming to City of Hope, Dr. Khan amassed significant medical leadership experience, most recently as the Chief of Hematology and Medical Oncology at St. Peter's Health Partners Medical Associates (SPHPMA) in Albany and Troy, New York. He also served on SPHPMA executive boards, chaired their Transfusion and Cancer committees and led their Breast Cancer Program Leadership committee.

Previously, at OSF St. Anthony Medical Center in Rockford, Illinois, he served as Medical Staff President and Medical Director of Oncology Services at the Patricia D. Pepe Cancer Center. Dr. Khan is excited to lead the Department of Medical Oncology at City of Hope Atlanta, Chicago and Phoenix by continuing to grow its practices, connecting with communities and providing personalized patient care.

Outside of City of Hope, Dr. Khan loves spending time with his son and his wife, who is a physician assistant. He enjoys swimming and biking and is a competitive runner who has completed multiple marathons and triathlons.
Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Apr 20, 2026
5.0
"Great Experience"
Apr 20, 2026
5.0
"Great Experience"
Apr 19, 2026
5.0
"Doctor Khan is the Best!! I love how caring he is. Also how he keeps on top of everything. He has been amazing during my journey so far."
Mar 31, 2026
5.0
"He is very caring"
Mar 20, 2026
5.0
"Excellent"
Mar 20, 2026
5.0
"Super excellent"
Mar 17, 2026
5.0
"Dr Khan is excellent"
Mar 10, 2026
5.0
"I've recommended City of Hope to family and friends. Currently I am getting my son in law to change to City of Hope for cancer treatment"
Mar 10, 2026
5.0
"Dr. Khan is an amazing oncologist. I have referred family members to City of Hope because of the care and treatment I am receiving. I wouldn't go anywhere else. Many people have asked why I travel so far when there are cancer centers much closer. It is because of Dr.Khan and my team of doctors and the care I receive at City of Hope."
Feb 28, 2026
5.0
"Dr.Khan is simply top notch!"
Feb 18, 2026
5.0
"Excellent"
Feb 18, 2026
5.0
"Excellent"
Feb 13, 2026
5.0
"Excellent"
Feb 13, 2026
5.0
"Great care"
Feb 3, 2026
5.0
"Dr. Khan is amazing!!"
Jan 23, 2026
5.0
"As I said before. City of hope is an amazing place and I tell everyone of the care received"
Jan 23, 2026
5.0
"Dr. Khan has been with me for three years now. Very knowledgeable, very confident which makes me make better decisions about my care. He is straight up with me and I like that. He excels in everything I have needed."
Jan 18, 2026
5.0
"There aren't enough positive, grateful words to explain Dr. Khan and his personable medical care. His compassion and knowledge along with his care is truly felt and seen from his heart. I'm sure he shows this to each of us as patients and we are all blessed to have him in our lives!"
Dec 31, 2025
5.0
"My son was in another state at the time of my appointment and my doctor had no problem with him calling and asking questions."
Dec 18, 2025
5.0
"Dr Khan is one of a kind. Best ever. I am 62 and have never met a doctor like him."
Nov 15, 2025
5.0
"Always recommend City of Hope when possible"
Nov 15, 2025
5.0
"Dr. Khan is the BEST doctor I've ever had. Very caring and loving even when he has to deliver not so good news. He's always prepared to give me the options of treatment"
Oct 22, 2025
5.0
"Wonderful"
Oct 22, 2025
5.0
"He is the best!!!"
Oct 18, 2025
5.0
"I will always recommend City Of Hope to anyone who has cancer. Everyone is so friendly. Even the patients."
Oct 18, 2025
5.0
"I love Dr. KHAN. He makes me feel like a person not a patient. He explains everything to me the way I understand it."
Oct 12, 2025
5.0
"Dr. Khan makes it worth the travel. I love the attention and time he takes to listen and fight for the best possible care and treatment. I love the ease of getting all my care at one facility. I don't have to take a month locally to get in all my visits that are accomplished there in a day"
Oct 11, 2025
5.0
"Dr. Khan and his team save my life and I will always be grateful he's professional and courteous and addresses all my concerns."
Oct 8, 2025
5.0
"Doctor Khan great"
Sep 6, 2025
5.0
"Dr Khan is "the man". A cool dude who knows his stuff and we love seeing him."
Aug 19, 2025
5.0
"I always recommend"
Aug 15, 2025
4.1
"Dr Khan talks more to my husband than he does to me. He's a great oncologist though"
Jul 21, 2025
4.7
"I think highly of the Dr. Because he respected me as a patient and gave me the best care to feel better physically."
Jul 14, 2025
5.0
"I just referred your clinic to a family member [...]!"
Jul 7, 2025
5.0
"All EXCELLENT"
Jul 7, 2025
5.0
"Excellent in everything. I have never experienced, felt or seen so much positive organization and professional excellence Even the cleanliness in all areas, disinfection stations in all places and the handling and use of gloves; It's impressive. I love it and I will do it super positive promotion"
Jul 2, 2025
5.0
"Dr.Khan is great. I recommended him to anyone"
Jul 1, 2025
5.0
"Awesome"
Jul 1, 2025
5.0
"Dr. Khan is great"