Second Opinion Consultation

A second opinion from City of Hope


(888) 552-6760

A second opinion from City of Hope helps you find the right answers

When you’re diagnosed with cancer, you want answers. You want them quickly, and you want them to help empower you to take control of your cancer care decisions. That’s why, at City of Hope, we get you the answers you need, with the urgency you deserve and the expertise to get it right.

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Discover the City of Hope difference

Our cancer care experts have extensive experience diagnosing and treating both early-stage and advanced-stage cancers, as well as complex and rare diseases. Our oncologists use a wide variety of standard-of-care and innovative treatment tools and technologies, including precision medicine breakthroughs in immunotherapy and targeted therapy drugs, to attack your specific cancer type, while also offering qualified patients access to clinical trials on potential new treatment approaches.

The cancer care experts at City of Hope work together, all under one roof, collaborating with you to confirm your diagnosis and recommend a treatment plan tailored to your specific diagnosis, needs and goals. These experts will continually monitor your progress, making changes as necessary in real time along the way.

At City of Hope, our whole-person care model means we’re not just treating the cancer. Our supportive care services are designed to help you manage side effects and improve and maintain your quality of life, so you can feel better while getting better. From nutritional support and pain management therapies to emotional and spiritual support, our supportive care services are designed to help keep you strong so you can continue your treatment plan without interruptions.

When you visit us, we do everything we can to make your time at our hospital as convenient and stress- free as possible. At City of Hope, your satisfaction and the quality of your experience are as important to us as delivering the personalized, comprehensive treatment you deserve—without having to worry about the logistics and the details. So you can have peace of mind—and confidence in the road ahead.


of patients say they would "definitely recommend" a City of Hope hospital.

“We called the toll-free number to inquire about a second opinion. Even from that first phone call, I felt well cared for. There were no voice prompts to wade through or shuttling from one person to the next. After meeting with the care team, I had a CT scan and was walked through a proposed treatment plan a day or so later.”

Rosie P, Colorectal cancer patient

Colorectal Cancer

“Discovering that I had options for cancer treatment was very empowering for me. Realizing that I can get a second opinion, as many opinions as I want, really, was vital to my recovery. I found a place that gave me the knowledge that I needed.”

Karin N, Breast cancer patient

Breast Cancer

“I knew I wanted a second opinion to find out if radiation was the best option for me. I met with a gynecologic oncologist, a radiation oncologist and other doctors and clinicians. Everyone I met with wanted to know what I thought and how I felt. It was so nice to be asked, and to know that I had a say in my treatment.”

Wendy S, Endometrial cancer patient

Endometrial Cancer

We’re available now to listen, hear your concerns and answer your questions.

Call us now to schedule your City of Hope second opinion appointment.

  • No out-of-pocket transportation costs for the patient and a caregiver*
  • Complimentary or greatly reduced lodging rates*
  • No hidden costs
  • No added financial stress
* If you’re a beneficiary of a government health insurance program, such as Medicare, City of Hope is not permitted to provide travel, lodging or transportation benefits.

Learn more about a City of Hope second opinion on your diagnosis and treatment plan

Getting a cancer diagnosis is just the beginning of a search for an accurate, comprehensive determination of the type, stage and extent of your disease. Discover some tips that may help you learn more about your cancer diagnosis.

How do I know if my cancer diagnosis is accurate? 

Receiving a cancer diagnosis is a life-changing event. Knowing you have options for your cancer care may help you feel more confident and in control. Explore six reasons why a second opinion matters.

Six reasons you should consider getting a second opinion 

Approximately 3.5 million women in the United States are living with a history of breast cancer, according to the American Cancer Society. If you’re one of them, you already know the disruptive role anxiety plays in a breast cancer diagnosis. Getting a second opinion for breast cancer may provide you with a more accurate diagnosis, access to innovative treatment options and peace of mind.

Does a second opinion for breast cancer make sense for you? 

Treatment for lung cancer is changing rapidly. Cancer research has led to new therapies, such as targeted therapy and immunotherapy, that have changed the outcome for many lung cancer patients. Those who are candidates for these treatments and whose cancer responds may live for years beyond what was previously possible. Get the information you need about your specific situation so you’re comfortable with your cancer care and treatment plan.

Compelling reasons to get a second opinion for lung cancer 

In 2008, Chris P. was diagnosed with stage 4 pancreatic cancer. She flew to City of Hope Chicago to receive a second opinion on her treatment options and chose to undergo a rigorous chemotherapy regimen. The shock of a cancer diagnosis can be overwhelming, but Chris found ways to keep moving forward. She shares the five steps that helped her process her diagnosis and navigate her cancer journey.

What now? Five steps you can take after a cancer diagnosis 

Whether you’re visiting a doctor for the first time, or seeking a second opinion, asking the right questions can help you to understand important information about your cancer diagnosis. Learn more about questions to ask your doctor during a medical appointment, so you’re better positioned to understand your diagnosis and cancer treatment options.

10 questions to ask your doctor during your first visit