The information on this page was reviewed and approved by
Maurie Markman, MD, President, Medicine & Science at CTCA.

This page was updated on April 2, 2021.

Metastatic melanoma

Once it spreads, or metastasizes, the disease is known as metastatic melanoma. This type of melanoma may typically occur during stage III or stage IV. Common sites for metastases include the lymph nodes, lungs, liver, bones and brain.  

Melanoma tumors that have metastasized to other parts of the body are still considered melanoma. For example, melanoma found in the lungs is called metastatic melanoma of the lung or melanoma with lung metastases.

Patients with metastatic melanoma may experience various symptoms depending on where in the body the cancer has spread. Metastatic melanoma symptoms and signs may include:

  • Fatigue
  • Swollen or painful lymph nodes
  • Weight loss
  • Loss of appetite
  • Trouble breathing or a cough that doesn’t go away
  • Bone pain
  • Headaches
  • Seizures
  • Swelling of the liver

Next topic: What are the stages of melanoma?