Karan Shah,MD, MBA


Radiation Oncologist and Co-Medical Director, Breast Program

Karan Shah, MD, MBA - Radiation Oncologist

The effects of cancer span a wide spectrum — physical, mental, emotional, social and even financial. City of Hope is unique in that it provides services to address all these aspects and more.

City of Hope Chicago
2520 Elisha Avenue
Zion, IL 60099
Radiation Oncology
Medical school:
Loyola University Chicago, Stritch School of Medicine, Maywood, IL
Radiation Oncology - Loyola University Medical Center, Maywood, IL
Advanced degrees:
MBA, Healthcare Management & Finance - Loyola University Chicago, Graduate School of Business, Chicago, IL
Academic Appointments

Assistant Clinical Professor, Department of Radiation Oncology

Radiation Oncology - American Board of Radiology
About Me

For Dr. Karan Shah, Radiation Oncologist at City of Hope Chicago, a career in medicine was the inevitable choice. “Being a doctor allows me to merge my interest in the human body with my desire to make a positive difference in the world,” he says. 

Born in India, Dr. Shah came to the United States at age 12. He completed his Bachelor of Science in Biology, with a minor in biostatistics and accounting, at Loyola University Chicago, where he also completed a Masters in Business Administration with concentration in healthcare management and finance. He completed his Doctor of Medicine at Loyola University Stritch School of Medicine in 2010, attending on a full-tuition merit scholarship and receiving the President’s Medallion for outstanding achievement in his final year.

Dr. Shah completed a Transitional Internship at Resurrection Medical Center in Chicago from 2010 to 2011. He completed his Residency in Radiation Oncology at Loyola University Medical Center, becoming Chief Resident in 2014.

During residency, Dr. Shah published original research on head and neck cancer and radiation oncology in several peer-reviewed medical journals. He authored a phase I protocol investigating the combination of intraoperative radiotherapy with kyphoplasty to treat spinal metastases. He is a member and serves on the Health Policy Council of the American Society for Radiation Oncology and he serves as Clinical Assistant Professor at the Rosalind Franklin University of Medicine and Science in North Chicago, Illinois.

Dr. Shah joined the radiation oncology department at City of Hope Chicago in August 2015. He has expertise in the use of 3D conformal radiation, intensity modulated radiation therapy, stereotactic radiosurgery, stereotactic body radiation therapy, intraoperative radiation therapy, brachytherapy, hyperthermia, and radiopharmaceutical therapy. Dr. Shah has a strong interest in clinical research and in particular, writing investigator-initiated clinical trials to examine new innovative approaches to treating cancer. “My overall goal is to be able to cure the cancer using the most optimal treatment modalities combined with an individual, patient-centered focus,” says Dr. Shah, “and to provide effective comprehensive cancer care.”

When he is not at City of Hope, Dr. Shah enjoys basketball, music, travel, leisure reading and spending time with family and friends.
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