Soft Tissue Sarcoma Cancer Patient

Soft tissue sarcoma

The information on this page was reviewed and approved by
Maurie Markman, MD, President, Medicine & Science at CTCA.

This page was updated on July 14, 2021.

Soft tissue sarcoma is a complex disease. Know your options.

Soft tissue sarcoma is cancer that develops in the tissues that support, connect or surround other structures and organs in the body, such as muscles, tendons, fat, blood vessels and nerves. Symptoms include a lump or mass, uncomfortable swelling, skin lesions and limited mobility. The disease is most often diagnosed in adults over the age of 50, in people with a weakened immune system and in those who have had exposure to some industrial chemicals.

At Cancer Treatment Centers of America® (CTCA), our cancer experts are trained and experienced in diagnosing and treating all stages of soft tissue sarcoma. After undergoing a biopsy, MRI, ultrasound or other diagnostic procedures to evaluate the disease, you will sit with a multidisciplinary team of doctors and clinicians who will work with you to develop a personalized treatment plan tailored to your needs and specific diagnosis. That plan will also include a range of supportive care therapies designed to help you manage the side effects of the disease and its treatment to support your quality of life.

What you should know after a soft tissue sarcoma cancer diagnosis

Treatment options

microscope being manipulated by scientist to view glass slide

Treatments for soft tissue sarcoma typically involve surgery, chemotherapy, radiation therapy or targeted therapy, or a combination of two or more of these approaches. Your multidisciplinary team of soft tissue sarcoma experts will answer your questions and recommend treatment options based on your unique diagnosis and needs.

Surgery is usually the first-line treatment for this type of cancer. The main forms of surgery for soft tissue sarcomas are wide local incision, amputation and laparoscopic surgery.

Chemotherapy may be used in combination with surgery and radiation therapy to treat advanced-stage disease.

Radiation therapy
Radiation treatments may also be used before (neoadjuvant therapy) or following surgery (adjuvant therapy).

Targeted therapy
Targeted therapy drugs are designed to seek out and kill specific tumor cells while sparing surrounding healthy cells.

Learn more about treatments for soft tissue sarcoma

Supportive care

Treatments for soft tissue sarcoma may cause a number of side effects, from pain and discomfort to nausea, neuropathy and fatigue. Our supportive care clinicians work with each patient to help prevent and manage side effects of the disease and its treatment—before, during and after regimens are delivered. Supportive care therapies for soft tissue sarcoma patients may include:


Behavioral health

​Our behavioral health support program is designed to support you and your caregivers before, during and after cancer treatment.


​Pain management

Pain management is a branch of medicine focused on reducing pain and improving quality of life through an integrative approach to care.


​Survivorship support

​Whether you are at one of our hospitals, or at home in between visits, CTCA is here to help. Members of your care team are only a phone call away.

Learn more
Todd Gillett

Todd G.

Soft Tissue Sarcoma

"From the get-go, I was impressed with the fact that CTCA had all of the types of health care providers I was looking for right there. In addition to oncologists, they had psychologists, naturopathic clinicians and other providers. I was thinking, 'Whoa, these people are on the same page as I’m on.' But first and foremost were the medical oncologist and radiation oncologist. After we met with them, I felt very comfortable."


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