This page was reviewed under our medical and editorial policy by
Maurie Markman, MD, President, Medicine & Science.
This page was updated on June 8, 2022.
Risk factors for gestational trophoblastic disease (GTD) may vary. Various risk factors associated with a woman’s pregnancy may increase her risk.
They include:
Age: Women who are younger than 20 or older than 35 at the time of conception may have a higher risk of developing GTD. Women who are over the age of 45 at the time they become pregnant may have an even higher risk.
History of molar pregnancy: Women who have had a previous molar pregnancy or who have a family history of molar pregnancy may have a higher risk of GTD.
History of miscarriage: Women who have had a miscarriage may have a higher risk of developing GTD.
Blood type: Women with an A or AB blood type may have a higher risk of GTD.
Learn more about treatments for gestational trophoblastic disease
Next topic: What are the symptoms of gestational trophoblastic disease?