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Gestational trophoblastic disease risk factors

This page was reviewed under our medical and editorial policy by

Maurie Markman, MD, President, Medicine & Science.

This page was updated on June 8, 2022.

Risk factors for gestational trophoblastic disease may vary

Risk factors for gestational trophoblastic disease (GTD) may vary. Various risk factors associated with a woman’s pregnancy may increase her risk.

They include:

Age: Women who are younger than 20 or older than 35 at the time of conception may have a higher risk of developing GTD. Women who are over the age of 45 at the time they become pregnant may have an even higher risk.

History of molar pregnancy: Women who have had a previous molar pregnancy or who have a family history of molar pregnancy may have a higher risk of GTD.

History of miscarriage: Women who have had a miscarriage may have a higher risk of developing GTD.

Blood type: Women with an A or AB blood type may have a higher risk of GTD.

Learn more about treatments for gestational trophoblastic disease

Next topic: What are the symptoms of gestational trophoblastic disease?

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