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Polyps

Polyps are common in the colon, rectum, intestines, stomach, nose and sinuses, ear canal and uterus. They may develop on any mucous membrane, including in the cervix, vocal folds and—rarely—in the urinary system and bladder.

This article will cover:

What are polyps?

Polyps are fleshy growths found on mucous membranes throughout the body. They may be flat against the tissue (sessile) or grow mushroom-like on a stalk (pedunculated). They’re typically smaller than a dime, but may vary in size from the head of a pin to the size of a ping-pong ball. Just one may be present, or many.

What causes polyps?

Most polyps don’t have a known cause. They may be due to inflammation or irritation from a foreign object. A family history of polyps or an inherited genetic syndrome or mutation may increase a person's risk.

How are polyps diagnosed?

Polyps don’t always cause symptoms, which is why regular screenings are important. Doctors may discover polyps through imaging tests such as X-rays, an ultrasound or a computed tomography (CT) scan. If polyps are thought to be along the digestive tract, the doctor may use a thin, flexible tube called an endoscope to see the lining of the intestines, stomach or throat.

Types of polyps

Polyps may appear in various parts of the body, and each type differs based on its location. Depending on where the polyp occurs, its symptoms and treatment options may differ.

Colorectal polyps

Though rectal and colon polyps don’t typically cause symptoms, they may occasionally cause bleeding, pain or digestive changes. Most colorectal polyps are noncancerous. Screening methods that detect polyps and colorectal cancer include a colonoscopy, virtual colonoscopy or blood tests.

Sometimes colorectal polyps develop because of an inherited syndrome, but typically there’s no known cause. Age plays a role, too. The risk for getting colorectal polyps increases as the patient gets older.

Gastric and stomach polyps

Most gastric and stomach polyps aren’t cancerous. Symptoms are rare and may include bleeding or pain from an obstruction in the digestive tract.

They’re often diagnosed with an endoscope, which is a lighted tube inserted through the mouth to see the inside of the digestive tract. Doctors may take a tissue sample to biopsy so they can determine the kind of growth.

Risk factors for stomach polyps include:

  • Bacterial infections, such as Helicobacter pylori (H. pylori) 
  • Rare genetic syndromes
  • Regular use of acid reflux medications called proton pump inhibitors (PPIs)

Uterine polyps

Endometrial polyps—those occurring in the lining of the uterus—are common, developing in 16 percent to 34 percent of people who have a uterus, according to a 2011 review in the Journal of Research in Medical Sciences.

Endometrial, or uterine, polyps may interfere with getting or staying pregnant, which is one way they’re discovered. They may also cause irregular, long or heavy bleeding during or between menstrual periods—or even after menopause.

Imaging tests to see inside the uterus are used to diagnose endometrial polyps. If found, the polyps may be biopsied and removed.

Researchers don’t know exactly what causes uterine polyps, but excess estrogen may play a role in their development. Uterine polyps are more likely to occur in women as they get older. Other factors may play a role as well, such as obesity, treatment for breast cancer with a drug called tamoxifen, hormone replacement therapies, or genetic conditions.

Cervical polyps

Polyps may also develop on the cervix, the opening between the uterus and the vagina. They don’t usually cause symptoms but may cause inflammation; heavy periods; bleeding after intercourse, after menopause or between periods; or a white or yellow mucus discharge.

For uterine and cervical polyps, medication may be recommended to shrink them. Cervical polyps may also be removed or cauterized. Samples of the polyp may be tested to determine whether the growth is cancerous.

Nasal polyps

Nasal polyps, which occur in the mucous membranes of the nose and sinuses, are typically benign growths. They may block the airway or cause stuffiness, a loss of smell or taste, snoring, a sinus infection or headache.

Risk factors for nasal polyps include:

  • Sinus infections
  • Allergies and asthma
  • Cystic fibrosis
  • Sensitivity to aspirin

Steroids may help treat nasal polyps, but they usually come back after treatment.

Throat and laryngeal polyps

These polyps develop inside the throat and on the larynx. Risk factors may include stressing the vocal cords, having acid reflux and smoking. Throat and laryngeal polyps may cause hoarseness. Rarely, they may make it difficult to breathe. Depending on their size and symptoms, they may be removed or just monitored.

Aural, or ear canal, polyps

Polyps may also grow in the ear canal, or even on the eardrum. The most common symptom is bloody drainage out of the ear, but polyps may also affect hearing. They may be caused by a skin cyst in the middle ear, a foreign object, inflammation or tumor. Medications include steroids and antibiotics.

Gallbladder polyps

Polyps that grow in the lining of the gallbladder are known as gallbladder polyps. They may cause such symptoms as nausea, trouble eating, fever, abdominal pain, jaundice and bloating.

Certain conditions may put patients at a higher risk for developing polyps in the gallbladder, including:

  • A history of gallstones
  • Cholangitis
  • Hepatitis B
  • Peutz-Jeghers Syndrome
  • Elevated cholesterol
  • Familial adenomatous polyposis (FAP)
  • Cholecystitis

Bladder polyps

When polyps form in the lining of the bladder, they may cause symptoms such as blood in the urine and painful or frequent urination.

Smoking and being male may increase a patient's risk for developing bladder polyps.

How are polyps removed?

Colorectal polyps: Polyps found during a colonoscopy or endoscopy may be removed as part of the procedure. In other areas of the body, doctors may want to biopsy the polyp to learn more. If doctors find and remove certain types of polyps, they may suggest another colonoscopy in three years, or sooner, as recommended by the American Cancer Society. Colorectal polyps recur 20 percent to 50 percent of the time, according to a 2020 review in Gut and Liver.

Gastric and stomach polyps: Polyps in this part of the body may be removed during the endoscopy when they're discovered.

Uterine polyps: The care team may remove uterine polyps during a procedure called a hysteroscopy.

Nasal polyps: Large polyps that cause symptoms may be removed with an endoscopic surgery.

Throat and laryngeal polyps: The surgeon may remove these nodules during surgery using a laryngoscope.

Aural, or ear canal, polyps: If medications don’t work, doctors may recommend surgery to remove these polyps.

Gallbladder polyps: If the care team determines that gallbladder polyps should be removed, they may need to surgically remove the entire gallbladder.

Bladder polyps: The surgeon may remove the polyps during a surgery called transurethral bladder resection (TURBT).

What happens if a polyp that is removed contains cancer?

Once the care team removes polyps, they’ll be sent to a pathologist for examination under a microscope. If cancer cells are found in the polyp, the patient and his or her care team will work together to develop a cancer treatment plan depending on the cancer type, location, stage and the patient’s overall health, among other potential factors.

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Show references
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