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Clinical-Trials

Clinical trials

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Cancer Treatment Centers of America® (CTCA) is committed to providing new and innovative treatments for our cancer patients whenever possible. This includes enrolling qualified patients in carefully selected clinical trials for cancer. Clinical trials are a key testing ground for determining the effectiveness and safety of new treatments and drugs for cancer and other diseases. Our doctors may recommend that cancer patients enroll in cancer clinical trials if they meet specific criteria. Cancer trials may offer patients access to treatment options that would otherwise be unavailable to them. Talk to your doctor about whether a cancer trial is a good option for you and ask about the risks and various requirements involved. Use the tool below to find a CTCA® clinical trial for your cancer type.

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26 Clinical Trials

     

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clinicaltrials.gov

The primary objective of this study for the safety run-in cohorts of the study is to evaluate the safety, tolerability, and recommended Phase 2 dose (RP2D) of magrolimab in combination with nab-paclitaxel or paclitaxel (safety run-in cohort 1), and sacituzumab govitecan (safety run-in cohort 2) in metastatic triple-negative breast cancer (mTNBC).

     

Accepting new patients

 

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clinicaltrials.gov

An open-label, randomized, phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab vs. chemotherapy in the second-line treatment setting in patients with colorectal cancer with KRAS G12C mutation.

     

Accepting new patients

 

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clinicaltrials.gov

A phase 2 study of magrolimab combination therapy in patients with head and neck squamous cell carcinoma

     

Accepting new patients

 

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clinicaltrials.gov

This is a phase 2 multicenter, open-label study evaluating the efficacy, safety, tolerability, and pharmacokinetics (PK) of RMC-4630 in combination with sotorasib in subjects with KRASG12C mutant NSCLC after failure of prior standard therapies.

     

Accepting new patients

 

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clinicaltrials.gov

This is a phase 2, open-label, multi-center study to evaluate the efficacy and the safety/tolerability of poziotinib in seven patient cohorts for up to 603 previously treated and treatment-naïve NSCLC patients.

     

Accepting new patients

 

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clinicaltrials.gov

This phase II/III Lung-MAP trial studies how well immunotherapy treatment with N-803 (ALT-803) and pembrolizumab working in treating patients with non-small cell lung cancer that has spread to other places in the body (advanced).

     

Accepting new patients

 

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clinicaltrials.gov

This is a global phase 2, multi-center, single-arm, open label study of taletrectinib in patients of NSCLC harboring with ROS1 fusion gene.

     

Accepting new patients

 

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clinicaltrials.gov

ATLAS-IT-05 is an open-label, single-arm study in patients with advanced melanoma accessible for injections (cutaneous, subcutaneous, lymph node, or intramuscular tumors) and who have either exhausted treatment options or are not eligible for, suitable for, or willing to undergo such treatments.

     

Accepting new patients

 

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clinicaltrials.gov

This study is a phase 1b/2, multi-center, open-label study in which patients with activating mutations in the RAS pathway (phase 1b) and patients with NRAS-mutated melanoma (phase 2) will be treated with a combination of oral OKI-179 combined with the MEK inhibitor binimetinib.

     

Accepting new patients

 

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clinicaltrials.gov

This is a randomized study of daratumumab plus lenalidomide vs. lenalidomide alone as maintenance treatment in patients with newly diagnosed multiple myeloma, who are minimal residual disease positive after frontline autologous stem cell transplant.