(888) 552-6760 SCHEDULE AN APPOINTMENT

Wade Smith,

M.D.

Medical Oncologist and Hematologist

4.8 (198 Ratings)
Biography photo
Location
Newport Beach
1601 Avocado Avenue
Newport Beach, CA 92660
Specialties
Breast Oncology
Medical Oncology
Education
Medical school:
Board Certifications
  • 2016, American Board of Internal Medicine

  • 2016, American Board of Medical Oncology

Degrees
  • 1995-1999, Doctor of Medicine, M.D., Creighton School of Medicine, Omaha, Nebraska

  • 1991-1995, Bachelor of Science, Biology (Cum Laude), Loyola Marymount University, Los Angeles, California

Fellowship
  • 2002-2005, Fellowship, Hematology/Oncology, Emory University School of Medicine (Winship Cancer Institute), Atlanta, GA

Residency
  • 2000-2002, Residency, Internal Medicine, Emory University School of Medicine, Atlanta, GA

Internship
  • 1999-2000, Internship, Medicine (categorical), Emory University School of Medicine, Atlanta, GA

Professional Experience
  • 2019-Present, Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research, City of Hope, Newport Beach and Duarte, California

  • 2012-2019, Medical Oncologist/Hematologist, Breastlink Medical Group, Orange, California

  • 2009-2011, Associate Physician, David Vafai, M.D., Inc., Rancho Mirage, California

  • 2008-2009, Physician, Southern California Permanente Medical Group – San Marcos, San Marcos, California

  • 2006-2007, Associate Physician, Hematology/Oncology, Cancer Center Oncology Medical Group, La Mesa, California

Academic Appointments
  • Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research
  • Director of Research, Newport Beach
About Me

Wade Michael Smith, M.D., is a medical oncologist and hematologist at City of Hope® Newport Beach, where he provides expert cancer care for a wide range of cancer types and serves as the location’s director of research. Dr. Smith brings years of training and experience to his role, and a philosophy founded on personalized, compassionate care. 

Dr. Smith earned his undergraduate degree in biology at Loyola Marymount University in Los Angeles. He went on to receive his medical degree from Creighton University in Omaha, Nebraska, then completed both his residency and fellowship at Emory University School of Medicine in Atlanta. He later returned to Southern California to continue his work helping patients through their cancer journey. 

While Dr. Smith treats a variety of cancers, he has a focus on treating breast cancer. His lifelong interest in biology has also led him to explore new treatments for cancers that do not respond well to conventional chemotherapy, and he is especially excited about helping bring these promising therapies from the lab into the clinic. 

Dr. Smith values how City of Hope has grown its presence in communities across Southern California while staying true to its mission of providing top-quality, patient-centered cancer care close to home.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
May 28, 2025
5.0
"Very good experience"
May 28, 2025
5.0
"Only very good people"
May 24, 2025
5.0
"Good"
May 23, 2025
5.0
"Dr. Smith said the entire team are wonderful"
May 22, 2025
5.0
"I visited Dr. Smith for a second opinion regarding my cancer medication treatment options."
May 16, 2025
5.0
"After receiving personally upsetting results from CTA, my provider acknowledged them with the best balance of listening and validating my concerns, discussing possible meanings, immediately addressing the need for more information and ending with whatever it is, based on possibilities, it will be manageable."
May 9, 2025
5.0
"Dr. Smith is the best Dr I could have ever been blessed with. He had been my rock through this Cancer Journey."
Apr 25, 2025
5.0
"GOOD"
Apr 25, 2025
5.0
"Like I said, this is a pleasant experience for going to a doctor office"
Apr 23, 2025
5.0
"Dr Smith found a study for me to join and it worked."
Apr 20, 2025
5.0
"Dr. Smith always listens, explains issues and has patience."
Apr 16, 2025
5.0
"Dr. Smith is the best"