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Vincent Mendiola,

M.D., M.P.H.

Medical Oncologist and Hematologist

5 (107 Ratings)
Biography photo
Location
City of Hope Santa Clarita
23823 Valencia Boulevard, Suite 250
Santa Clarita, CA 91355
Education
Medical school:

Doctor of Medicine, University of Miami Miller School of Medicine, Miami, FL

Residency:

Internal Medicine - University of Texas Medical Branch, Galveston, TX

Academic Appointments
  • Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research
About Me

Vincent Louie Mendiola, M.D., M.P.H., M.Sc., is a medical oncologist and hematologist with a strong background in research and public health. At City of Hope® Santa Clarita, he listens to patients so he can fully understand their values, concerns and goals, and develops personalized treatment plans based on a physician-patient partnership. He’s motivated by the rapid progress happening in cancer care and is passionate about bringing those benefits directly to his patients. 

Dr. Mendiola is committed to improving treatment outcomes by combining high-quality clinical care with research and public health knowledge — especially when it comes to reducing disparities in cancer care. His 15 peer-reviewed scientific papers have shown that minorities with an aggressive form of leukemia can achieve the same outcomes as others when they receive equal access to all current standards of care and new therapies. He has also engaged in health outreach programs in the Philippines and Nicaragua and was honored by the Department of Health for designing a mobile clinic for the HIV/STD Prevention Program while earning his Master of Public Health at the University of Miami. 

Outside of work, Dr. Mendiola enjoys food from different cultures and playing basketball.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Jul 15, 2026
"Good experience"
Jul 3, 2026
5.0
"This provider was absolutely excellent [...]. He more than made up for any doubts, gaps or miscommunications on care in my complete care cycle to 2019. Refreshing exchange."
Jul 3, 2026
5.0
"Takes his time to explain and very knowledgeable about the treatment plan in case it is needed in the future. Very professional and easy to understand. Glad that I switched."
Jul 3, 2026
5.0
"Dr Mendiola is an excellent physician, and a great listener who really cares about you . He makes sure that you understand everything with easy to comprehend explanations. He is a role model for how physicians should interact with patients. I feel blessed to have him as my care provider!!"
Jul 2, 2026
5.0
"I recommend Dr. Mendiola quite frequently. He is very thorough."
Jul 2, 2026
5.0
"Dr Mendiola is superb about explaining everything. I feel very comfortable with him and his care. He lets me decide but explains options for comfort."
Jun 26, 2026
5.0
"Totally recommend 100%"
Jun 23, 2026
5.0
"Dr Mendiola is a very compassionate physician and he always makes me feel completely seen and heard"
Apr 17, 2026
5.0
"Dr Mendiola is a top problem solver and has a good personality and perspective."
Apr 17, 2026
5.0
"We worked out problems together and are trying something different."
Mar 29, 2026
4.4
"At times I felt overwhelmed as I dealt with the scope of what my condition could be. The doctor did his best to put me at ease and explain things."
Mar 26, 2026
5.0
"Thank you to Dr. Mendiola for his caring."
Mar 17, 2026
5.0
"Dr Mendiola and staff are all excellent and I have already recommended COH to others."
Mar 5, 2026
5.0
"Excellent Physician. He gave specific guidance to all the questions I asked.His expertise and knowledge are very valuable to overall health."
Mar 5, 2026
5.0
"Excellent doctor with full knowledge in pharmacological medicines.Explains all medications I'm currently taking and how they affect each other."
Feb 6, 2026
5.0
"You guys are the best!"
Feb 6, 2026
5.0
"Dr Mendiola is great! He saved my brother's life with stage 4 cancer. He is concerned that I will have the same problem and is very attentive to monitoring my health."
Dec 31, 2025
5.0
"First doctor that I felt cared about me. Love him"
Nov 19, 2025
5.0
"Wonderful"
Nov 16, 2025
5.0
"City of Hope and the team in charge of me has saved my life"
Nov 14, 2025
5.0
"Dr Mendiola is an excellent doctor"
Nov 10, 2025
5.0
"No long waiting, questions are answered. Very nice to talk to."
Nov 10, 2025
5.0
"Good experience . I want my Dr to treat me"
Oct 19, 2025
5.0
"Dr Mendiola remember to check on past issues that are ongoing."
Oct 16, 2025
5.0
"Good"
Oct 16, 2025
5.0
"Good"
Oct 11, 2025
5.0
"You are all the greatest."
Oct 11, 2025
5.0
"Dr Mediola is an excellent professional, very competent and very personable."
Oct 11, 2025
5.0
"Very grateful for the service provided by the whole team"
Oct 3, 2025
4.9
"Dr Mendiola has excellent "bed side manner". He was very clear and engaging. Listened extremely well and very responsive. His explanations were some of the very best I've heard from a doctor. As a care giver for both parents, unfortunately, I had a lot of confusing conversations with expert docs in the past. Dr. Mendiola ranks the highest in his ability to explain complex info quickly and easily. [...] initial take is VERY good."