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Sean Szeja,

M.D., M.S.

Radiation Oncologist

4.9 (120 Ratings)
Biography photo
Location
City of Hope Upland
1100 San Bernardino Road, Suite 1100
Upland, CA 91786
Specialties
Radiation Oncology
Education
Medical school:

2013, Doctor of Medicine, University of Arizona, College of Medicine, Tucson, Arizona

Residency:

2014-2018, Resident, Radiation Oncology, University of Texas, Medical Branch, Galveston, Texas

Academic Appointments
  • Assistant Clinical Professor, Department of Radiation Oncology
About Me

Board-certified radiation oncologist Sean S. Szeja, MD, MS, serves patients with a wide range of cancer types at City of Hope® Upland, bringing expertise in advanced radiation therapy techniques. 

Originally from Florida, Dr. Szeja moved to Southern California to attend Caltech, where he double-majored in physics and economics while conducting research at NASA’s Jet Propulsion Laboratory, before completing a master’s degree in mathematics at the University of Chicago. After earning his medical degree at the University of Arizona in Tucson, Dr. Szeja took on an internship at the University of Nevada in Reno, then completed his residency in radiation oncology at the University of Texas Medical Branch in Galveston, which included rotations at MD Anderson Cancer Center and Houston Methodist Hospitals. During his final year, he served as chief resident and received the Roentgen Resident Research Award from the Radiological Society of North America. 

Dr. Szeja has co-authored numerous studies on lymphoma and cancers of the breast, lung and colon. His research on the benefits of radiation therapy in older patients with triple-negative breast cancer was recognized by the American Society of Clinical Oncology’s Breast Cancer Symposium.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Apr 28, 2026
"All very well thanks"
Apr 25, 2026
"Dr Szeja is a proficient professional who treats his patients with courtesy and respect he truly is one of the best."
Mar 28, 2026
5.0
"My husband and I love Dr. Szeja. He is incredibly easy to talk to and approachable. It's like going to your brother for medical treatment. He listens and explains his responses like a teacher. He will pull up graphics on his computer to help illustrate what he means. I feel very fortunate to have him as my radiology physician. He was concerned about my healing and prescribed a couple of medications to encourage the process. I'm grateful for his care of my well being."
Mar 23, 2026
5.0
"Dr actually called and reached out to me .. It was perfect."
Feb 13, 2026
5.0
"COH is the best."
Jan 26, 2026
5.0
"Not rushed and atmosphere was they cared."
Jan 24, 2026
5.0
"Good"
Jan 24, 2026
5.0
"Good"
Jan 8, 2026
5.0
"Doctor keep referring me to my oncologist . It seems he does not know about my condition . My question is regarding radiation that was done thru his department . All issues u am concerns are all about the radiation . Is affecting my bones and body and he does not know what to answer except you can ask [...] on that ??? It's about radiation effect on my hips and thighs and legs so my concern didn't get treated fir something he dies not know anything at all ????"
Nov 29, 2025
5.0
"Dr. SZEJA has taken my case from [...], this is the first time I have met Dr. SZEJA, and I appreciated his introduction and visit with me while I was being "fitted" for table used for radiation therapy. By taking time to introduce himself he removed any concerns, worries or anxiety."
Nov 28, 2025
5.0
"Cancer treatment and radiation are never easy, Dr Szeja makes it easy to understand and I am so grateful!"
Nov 28, 2025
5.0
"Everyone in this office works very closely to give us patients the best service and care possible given our circumstances, whomever put this team together has done a great job! I love City of Hope!"
Nov 25, 2025
5.0
"Dr. Szeja is a very knowledgeable and kind doctor. He was extremely thorough in his overview of the post-surgery treatment plan recommended for me. He described what would take place, how it is to be performed on my affected area, my right breast. He described any side effects of the radiation that I may experience, and how long they may last, if I experience the side effects. Dr. Szeja is very personable, caring, and gave me and my husband the impression that he is concerned about his patients."
Nov 20, 2025
5.0
"Good"
Nov 20, 2025
5.0
"Good"
Nov 4, 2025
5.0
"Dr Szeja was excellent! Very informative and caring! Extremely happy I will be in his care"
Oct 7, 2025
5.0
"Everyone says how wonderful City of Hope is if you get a cancer diagnosis, and I must concur. Everything works like clockwork, and everyone, from the receptionists to the nurses to the doctors are so highly professional and tender and caring. Gosh, what wonderful treatment during such a tough time! THANKS!"
Oct 7, 2025
5.0
"Gosh, I never hope I have to refer anyone to the most excellent Cardiac Radiologist Dr. Szeja, but let me say, he was so very kind and polite, and informative and professional, and explained all options, treatments, and procedures in great detail showing us books and pictures and diagrams, and he elicited the greatest confidence and respect in what I am about to go through these nasty radiation treatments, so I have nothing but the utmost respect and highest regard for Dr. Szeja. He also explained how useful this radiation treatment will be, add gave us all the stats as to recurrences and survivability rates; we could not have asked for a better doctor to work with, and it is our honor to be treated by Dr. Szeja."
Sep 30, 2025
5.0
"Dr Sean Szeja is compassionate and extremely knowledgeable. I loved how he always took the time to explain my questions and would even show me pictures in his books so I was able to understand even more! I'm so blessed he was part of my journey!"
Sep 27, 2025
5.0
"One of the best, if not the best, physicians I have ever met with, and I've met with several over my almost 70 years. Dr Szeja is intelligent, courteous, professional and very organized. His explanation of my situation was the clearest of any meeting I have ever had with a physician. City of Hope is so lucky to have this man!"
Sep 23, 2025
5.0
"All my experiences were good!"
Sep 17, 2025
5.0
"Very helpful"
Sep 17, 2025
5.0
"Very good experience"
Sep 14, 2025
5.0
"Excellent Dr Szeja cared about me immediately contacted City of Hope Duarte and sent me to the Emergency Room in Duarte"
Sep 1, 2025
5.0
"Great"
Sep 1, 2025
5.0
"Great"
Sep 1, 2025
5.0
"Dr Sean is a great doctor in all aspects, he's a good listener and cares for his patients"
Aug 30, 2025
5.0
"Very good experience"
Aug 30, 2025
5.0
"Very good experience"
Aug 28, 2025
4.7
"Thank you very well"
Aug 28, 2025
4.7
"Excellent attention from the Doctor thank you"
Aug 25, 2025
5.0
"Dr. Szeja was very thorough and wanted to make sure he had all my information."
Jul 29, 2025
5.0
"Very helpful"
Jul 29, 2025
5.0
"Very professional"
Jul 29, 2025
5.0
"Very concerned about my health. Very helpful for me"