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Percy Lee,

M.D.

Radiation Oncologist

4.9 (150 Ratings)
Biography photo
Location
City of Hope Orange County Lennar Foundation Cancer Center
1000 Five Point
Irvine, CA 92618
Specialties
Radiation Oncology
Education
Medical school:
  • 1998–2003, M.D., Division of Health Science and Technology, Harvard Medical School — Boston, MA
  • 1994–1998, B.S., Biomedical Engineering, John Hopkins University — Baltimore, MD
Residency:
  • 2004–2008, Radiation Oncology, Stanford University School of Medicine — Stanford, CA
Academic Appointments
  • Vice Chair of Clinical Research, Department of Radiation Oncology
  • Medical Director of Orange County & Coastal Region Radiation Oncology
  • Professor, Department of Radiation Oncology
About Me

Percy Lee, M.D., is a professor of radiation oncology at City of Hope, where he also serves as vice chair of clinical research in the Department of Radiation Oncology and medical director of Orange County and Coastal Region Radiation Oncology. A compassionate physician with nationally renowned expertise in his field, Dr. Lee takes a team approach to cancer care, working closely with other specialists to create a treatment plan that's personalized to each patient’s medical history, emotional wellbeing and unique diagnosis. 

Dr. Lee graduated magna cum laude from Harvard Medical School’s Health Sciences and Technology program, a collaboration with the Massachusetts Institute of Technology. During his training, he was also a research fellow with the Howard Hughes Medical Institute in Chevy Chase, Maryland, where he studied how tumors use blood vessel growth to spread. He went on to complete an internal medicine internship at Massachusetts General Hospital, followed by a radiation oncology residency at Stanford University in California, where he also served as chief resident. 

In the clinic, Dr. Lee specializes in treating cancers of the lung and gastrointestinal tract. As medical director of radiation oncology for City of Hope® Orange County Lennar Foundation Cancer Center and vice chair for clinical research in the Department of Radiation Oncology, he focuses on expanding access to advanced radiation treatments and research for patients across Southern California. 

Before joining City of Hope, Dr. Lee held leadership roles at MD Anderson Cancer Center in Houston, Texas, where he helped shape clinical and research priorities, and at the University of California, Los Angeles, where he led programs in stereotactic body radiation therapy and MRI-guided radiation therapy. 

Fluent in Mandarin, Dr. Lee is proud to care for patients in his native Southern California. When not working, he enjoys spending time with his wife and two children, as well as playing basketball with friends.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Mar 21, 2026
"Dr Percy P Lee was great. Thoughtful and caring. Listen to our concerns and discussed different options"
Mar 18, 2026
4.9
"Dr. Lee is very knowledgeable and a good communicator. He took care to explain medical terms in language I could easily understand. He spent time doing that and didn't rush me out the door."
Mar 15, 2026
5.0
"Good"
Mar 15, 2026
5.0
"Good"
Feb 15, 2026
5.0
"It's pretty cool to leave a cancer center feeling invigorated."
Feb 5, 2026
5.0
"Listening and explaining"
Jan 30, 2026
5.0
"The physician who saw me was professional, efficient, and friendly."
Jan 24, 2026
5.0
"Dr. Percy P. Lee is extremely knowledgeable. He had carefully researched my health records and outlined a superior plan for treatment. I trust him completely."
Jan 13, 2026
5.0
"Good"
Jan 13, 2026
5.0
"Good"
Nov 22, 2025
5.0
"Very professional and Caring"
Nov 13, 2025
5.0
"Specifically about Dr. Percy Lee: From the moment the consultation began, I was profoundly impressed. Dr. Lee embodies a rare combination of elite academic preparation and substantial career experience garnered from a top-tier facility. I had specifically requested him based on my extensive research, and he was honored and obliged to grant my wish for this appointment.His wide-ranging expertise in the field is evident, yet it is delivered with a refreshing calmness and composure, not a hint of excessive confidence, which immediately put me at ease. He demonstrated an intuitive ability to sense my concerns, addressing both the spoken questions and the unspoken anxieties before I could articulate them.I was particularly struck by his meticulous approach: he flawlessly recounted a synopsis of my complex medical history verbatim without relying on notes (and I thought I had a great memory!), a testament to his preparation and focus. Furthermore, he articulated a clear roadmap for what I should expect to experience, ensuring absolute clarity.The facility and state-of-the-art equipment are superb, but the specialist's conduct is the true highlight. His genuinely friendly and caring demeanor, combined with his appreciation for the search I had already done, solidified my trust. He ensured every question was answered, providing a continuous line of support moving forward.This is more than a specialist; he is a truly masterful guide. Highly recommended. Thank you, Dr. Lee!"
Oct 7, 2025
5.0
"I feel great about the care that Dr Lee provides"
Oct 7, 2025
5.0
"Dr Lee has been on my team since early 2024 and has done treatment on my lung, rib, prostate and brain. He is prolonging my life, and quality of life!"
Oct 6, 2025
3.1
"Kept looking at watch"
Sep 25, 2025
5.0
"The staff members treat everyone with BIG smile and very kind reception."
Sep 25, 2025
5.0
"Dr Percy Lee is very good and professional. I am so lucky to have him treated."
Sep 23, 2025
5.0
"Excellent"
Sep 18, 2025
4.7
"I love the City of Hope"
Sep 2, 2025
4.4
"Good"
Sep 2, 2025
4.4
"Good"
Aug 14, 2025
5.0
"Dr Percy Lee spent quite a bit of time explaining the process of mapping for the pancreatic cancer -- we were very impressed"
Aug 12, 2025
5.0
"Dr. Lee is a consummate professional. He has always been very attentive to my condition and has explained all issues with my condition throughout my treatment. He has a kind way with patients, which is a real benefit when going through treatment for cancer."
Aug 12, 2025
5.0
"The City of Hope has an amazing corporate culture. From the people that greet you at the desk to the assistant/nurses, and the doctors everyone is very caring, helpful, and professional. The Hospital should be proud of this culture because it is often very hard to infuse a caring attitude throughout such a large organization."
Jul 29, 2025
5.0
"Always caring and understanding"
Jul 8, 2025
5.0
"Outstanding Doctor."
Jul 8, 2025
5.0
"I couldn't be happier with City of Hope and that is 100% due to the staff and my oncology team. They have just been exemplary in every aspect of my care."
Jun 29, 2025
5.0
"Good"
Jun 29, 2025
5.0
"Good"
Jun 24, 2025
5.0
"Thank everyone for their phenomenal care!"
Jun 24, 2025
5.0
"I literally just got off the phone recommending someone to Dr. Percy Lee! [...]"
Jun 20, 2025
4.9
"No real concerns I've already referred both [...] and Dr. Lee to a few of my friends that are now currently seeing them"
Jun 6, 2025
5.0
"Dr. Percy Lee was beyond anything I could have hoped for. Gave me clear understanding, set up a positive and immediate plan for my cancer, spent time with my wife and I along with his uber-capable assistant, [...]."