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Nishan Tchekmedyian,

M.D., M.B.A

Medical Oncologist and Hematologist

5 (151 Ratings)
Biography photo
Location
City of Hope Orange County Lennar Foundation Cancer Center
1000 Five Point
Irvine, CA 92618
City of Hope Seacliff
2100 Main Street #300
Huntington Beach, CA 92648
Specialties
Hematologic Oncology
Medical Oncology
Education
Medical school:
  • 2024, MBA, Business School Anderson School of Management, University of California, Los Angeles, CA
  • 2010, Doctor of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA
  • 2006, BA, University of California, Los Angeles, Business Economics
  • 2006, BS, University of California, Los Angeles, Molecular, Cell and Developmental Biology
Residency:
  • 2010-2013, Intern and Resident in Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA
Academic Appointments
  • Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research
  • Deputy Physician-in-Chief, City of Hope Orange County
About Me

Dr. Nishan Tchekmedyian is a medical oncologist and hematologist at City of Hope®, where he also serves as deputy physician-in-chief for City of Hope’s Orange County Lennar Foundation Cancer Center

A compassionate and dedicated physician, Dr. Tchekmedyian has been honored multiple times by Greater Newport Physicians for his commitment to excellent, patient-centered care, being named New Physician of the Year in 2017 and Specialist of the Year for three years in a row (2019–2021). 

Dr. Tchekmedyian completed his medical degree at the David Geffen School of Medicine at the University of California, Los Angeles. He went on to pursue internal medicine training at Beth Israel Deaconess Medical Center at Harvard Medical School, then a medical oncology and hematology fellowship at the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida. His research has helped explore new cancer treatment options for patients, including immunotherapy for advanced prostate cancer and targeted therapy for a rare genetic mutation found in lung and other cancers. 

Dr. Tchekmedyian is fluent in Spanish and Armenian.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Apr 30, 2026
5.0
"Dr.Nishan Tchekmedyian is a brilliant physician and an incredibly caring human being."
Apr 4, 2026
5.0
"Dr. T and everyone on staff have always been very courteous and accomodating to any schedule changes I have requested. The doctor has been very thourough and answered questions I have asked very clearly. I am very satisfied with the treatment plan he instituted and the results to date. I highly reccomend City of Hope and specifically this location and staff to anyone in need of treatment."
Apr 3, 2026
5.0
"As always, Doctor Nishan was thorough and personable. He's a great doctor and an awesome human being. I am lucky to have him."
Apr 1, 2026
5.0
"Dr. Nishan is wonderful. I have specialized bloodwork routinely. As soon as he gets the results he messages me and lets me know. I don't have to wait until my next appointment. I am so very grateful for that. Thank you Dr. Nishan."
Mar 14, 2026
5.0
"Dr. Tchekmedyian is the best of the best, extremely knowledgeable, experienced, kind, patient, and caring."
Mar 9, 2026
5.0
"Dr Nishan and team are outstanding medical professionals"
Mar 6, 2026
5.0
"Dr. Nishan is awesome!!"
Feb 13, 2026
5.0
"Everything went well"
Feb 13, 2026
5.0
"Everything went very well"
Feb 7, 2026
5.0
"After our initial contact with Dr. NISHAN TCHEKMEDYIAN, It has been very good with the Dr and the nurses follow up!"
Feb 4, 2026
5.0
"Dr. NISHAN is excellent. I consider myself fortunate to have him as my oncologist."
Jan 25, 2026
5.0
"From the Ambassadors, to the lab staff and phlebotomists, to the nurses and especially the Practitioners, I feel very well cared for. They all work together so well as a team. I consider myself very lucky and valued."
Jan 25, 2026
5.0
"Dr Tchekmedyian has been my Hematologist for 7 years. During that time he has provided exemplary care to me, even saving my life. He is very aware of my health history, my medications, changes in my condition, and is so caring! He plans together with me for my treatment and optimal health and wellness. I am very grateful and thankful for him!"
Jan 9, 2026
5.0
"I have recommended multiple people to Dr Nishan and they are as impressed with him as I am"
Jan 9, 2026
4.7
"Dr. Nishan's care is excellent. He is extremely will informed and pays attention to details about my care."
Jan 2, 2026
4.7
"On time, gentle, frendly, caring, human with a capital H ,trustwordy."
Jan 2, 2026
4.7
"He spent over 1 hour time with us. We leave far and he understood our situation and offered to just care for my husband over screen instead of driving 1.5 hour. We are really pleased."
Nov 15, 2025
5.0
"I have referred my daughter"
Nov 4, 2025
5.0
"Perfect"
Oct 24, 2025
5.0
"Doctor Nishan is very dedicated physician, he's listening to patients, answering all their questions, in a very calm way & with a smile."
Oct 8, 2025
5.0
"Dr. Nishan is an excellent communicator."
Oct 6, 2025
5.0
"Dr. T is the BEST!"
Oct 6, 2025
5.0
"Already have I referred patients!"
Sep 12, 2025
5.0
"An excellent doctor!!"
Sep 1, 2025
5.0
"Dr. Nishan is fantastic!"
Jul 19, 2025
5.0
"Highly recommend"
Jul 19, 2025
5.0
"One of the best knowledgeable Dr I know."
Jul 13, 2025
5.0
"The entire team worked together for care and made sure he received the best care possible. Very good team! Thank you!"
Jul 13, 2025
5.0
"The provider is excellent, very friendly, attentive and very professional. He is very knowledgeable about the subject. It is the best provider we have met to date."
Jul 6, 2025
5.0
"Dr. Tchekmedyian is absolutely the BEST! Knowledgeable, experienced, kind, patient, humble, he is the best of the best and I am so blessed and so lucky he is my doctor"
Jul 4, 2025
5.0
"Excellent provider. Very satisfied with the visit."