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Murali Janakiram,

M.D., M.S.

Hematologist-Oncologist

5 (124 Ratings)
Biography photo
Location
City of Hope Comprehensive Cancer Center - Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Hematologic Oncology
Education
Medical school:

M.B.B.S., Madras Medical College

Residency:

Internal Medicine - Case Western Reserve University — Metro Health Medical Centre, Cleveland, OH

Academic Appointments
  • Associate Professor, Department of Hematology & Hematopoietic Cell Transplantation
About Me

Murali Janakiram, M.D., M.S., is a hematologist-oncologist at City of Hope® Cancer Center Duarte, where he works closely with patients diagnosed with multiple myeloma and other blood disorders. Dr. Janakiram’s philosophy is founded in developing personalized treatment plans that take medical and social factors into account, thereby ensuring that patients receive whole-person care. In addition to supporting his patients through every step of their cancer journey, Dr. Janakiram is committed to shaping the next generation of therapies through innovative research. 

Particularly devoted to advancing care for patients with multiple myeloma, Dr. Janakiram is focused on integrating novel treatments such as minimal residual disease-guided, limited-duration therapies and leading-edge immunotherapies like bispecific antibodies and CAR T-cell therapy into his approach to care. As a clinical investigator with more than 50 peer-reviewed publications, reviews and book chapters, he has developed risk-adapted strategies for treating myeloma and is actively exploring how best to sequence immunotherapies and prevent disease recurrence after treatment. 

Dr. Janakiram earned his medical degree at Madras Medical College in India and a master’s degree in clinical research at Albert Einstein College of Medicine in New York City, where he later completed his fellowship in hematology-oncology. His internship and residency took place at Metro Health Medical Center in Cleveland, Ohio.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Mar 31, 2026
5.0
"I am extremely grateful for the Doctors clear explanation of my condition and treatment"
Mar 25, 2026
5.0
"Highly recommend! City of Hope is a well run institution."
Mar 25, 2026
5.0
"Dr. Janakiram is a very bright, well-read physician who listens well and has been the key person in helping me remain productive. So much so, I dedicated my recent book on cancer to him."
Feb 5, 2026
5.0
"Excellent visit laying out a detailed play of next steps."
Jan 22, 2026
5.0
"Dr. Janakiram is an outstanding, knowledgeable and compassionate physician"
Dec 9, 2025
5.0
"Excellent"
Dec 9, 2025
5.0
"Beyond excellent"
Nov 14, 2025
5.0
"I thank the City of Hope for a wonderful experience"
Oct 23, 2025
5.0
"Dr Janakiram is an absolute gift, he listens and is "present" addressing my condition. I am blessed to have him as my Hematologist. Thank you!"
Oct 18, 2025
5.0
"Great care"
Oct 18, 2025
5.0
"I have a wonderful care team"
Oct 16, 2025
5.0
"Clone Dr. Janakiram"
Sep 25, 2025
5.0
"Good experience"
Sep 25, 2025
5.0
"Very good experience"
Sep 12, 2025
5.0
"Dr Janakiram was always able to give me the best possible treatment options while considering my condition and my daily life."
Sep 2, 2025
5.0
"I feel completely taken care of."
Sep 1, 2025
5.0
"Dr Janakiram always has a good handle on my individual situation and needs. I had specific questions, and he was able to provide detailed responses. He was prepared for our meeting, and provided me with all the info I needed for changing meds, vaccines, etc."
Aug 30, 2025
5.0
"I would certainly recommend city of hope."
Aug 30, 2025
5.0
"I've only had my first date with him, but it was very good for me, from every point of view, emotionally, and rationally. My treatment began and little by little other explanations will come, I understand that."
Aug 19, 2025
5.0
"Dr. Janakiram is a wonderful doctor, compassionate and very knowledgeable. I feel blessed to have him as my physician."
Aug 12, 2025
5.0
"They care that you understand everything"
Aug 12, 2025
5.0
"Yes, I would recommend it. In fact, I always wanted to be treated in this hospital."
Jul 25, 2025
5.0
"Very good"
Jul 25, 2025
5.0
"Very good"