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Mary Cianfrocca,

D.O., M.B.A.

Medical Oncologist

4.9 (26 Ratings)
Biography photo
Location
City of Hope Comprehensive Cancer Center - Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Breast Oncology
Medical Oncology
Education
Medical school:
  • 1989, Doctor of Osteopathy, Valedictory Honors Distinction, Chicago College of Osteopathic Medicine, Downers Grove, Illinois
Residency:
  • 1993–1994, Chief Resident, Rush Presbyterian St. Luke’s Medical Center, Chicago, Illinois
  • 1990–1993, Resident, Department of Internal Medicine, Rush Presbyterian, St. Luke’s Medical Center, Chicago, Illinois
Academic Appointments
  • Professor, Department of Medical Oncology & Therapeutics Research
  • Senior Medical Director, Community Practices
About Me

Mary Cianfrocca, D.O., M.B.A., has dedicated her career to breast cancer care and research, with a passion for finding better treatments and, ultimately, a cure. She brings more than 20 years of experience to City of Hope®, where she serves as senior medical director of community practices. 

A seasoned expert in breast cancer treatment and clinical research, Dr. Cianfrocca works closely with her patients at City of Hope locations in Duarte and Antelope Valley to provide optimal care while also exploring new options like targeted therapies and immunotherapy. 

She earned her medical degree at Chicago College of Osteopathic Medicine and trained at Rush Presbyterian St. Luke’s Medical Center and Northwestern University. In addition, she holds an M.B.A. from Arizona State University. 

Before joining City of Hope, Dr. Cianfrocca held leadership roles for nearly a decade at Banner MD Anderson Cancer Center in Arizona. She is also active in raising awareness about breast cancer prevention and early detection and regularly engages with the media as a subject matter expert. 

She strongly believes in City of Hope’s team-based approach, where doctors and specialists collaborate to deliver the most advanced and compassionate care to patients and their families.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Mar 19, 2026
5.0
"Dr. Cianfrocca is a wonderful, very patience, professional and humble."
Oct 8, 2025
5.0
"Dr. Cianfrocca is the best doctor I've ever had an appointment with. [...]"
Aug 20, 2025
5.0
"[...] I would definitely recommend her."
Jun 23, 2025
5.0
"[...] nurses and doctors everyone is very nice and helpful"
Jun 23, 2025
5.0
"Dr. Cianfrocca is very kind. Very good and I like her way of making me feel good and gives me positive vibes."
Jun 18, 2025
5.0
"Prior to me going to the City of hope I had heard good things. I am very pleased to be switching health care providers Dr Cianfrocca was wonderful and I actually am looking forward to having her as my DR"