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Luke N. Ledbetter,

M.D.

Neuroradiologist

Biography photo
Location
City of Hope Comprehensive Cancer Center - Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Neurology
Education
Medical school:

2008, Doctor of Medicine, Saint Louis University School of Medicine, St. Louis, Missouri Fellowship

Residency:

2013, Diagnostic Radiology, University of Kansas Medical Center, Kansas City, Kansas

Academic Appointments
  • Clinical Professor, Department of Diagnostic Radiology
  • Section Chief, Division of Neuroradiology
About Me

Luke Ledbetter, M.D., is a neuroradiologist who brings both professional expertise and personal perspective to his work. Having supported a close family member through metastatic cancer, he understands the importance of seeing each patient as an individual with their own story and needs. As a specialist in head and neck imaging, he uses the most advanced techniques to help guide accurate diagnosis and treatment planning. 

Dr. Ledbetter earned his medical degree at St. Louis University of Medicine, where he also completed an internal medicine internship. He went on to complete a diagnostic radiology residency at the University of Kansas, serving as chief resident, followed by an intensive two-year neuroradiology fellowship at the University of Utah, where he was named fellow of the year. 

A dedicated physician and researcher, Dr. Ledbetter has co-authored more than 30 peer-reviewed biomedical publications and helped shape national guidelines through the American College of Radiology. Before joining City of Hope® in 2024, he led head and neck imaging at UCLA, where residents honored him as associate professor of the year, and served as neuroradiology section chief and endowed professor at the University of Kansas. He is also a past president of the Western Neuroradiology Society.

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