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Leslie E. Botnick,

M.D.

Radiation Oncologist

4.9 (73 Ratings)
Biography photo
Location
City of Hope Sherman Oaks Radiation Oncology
5522 Sepulveda Boulevard
Sherman Oaks, CA 91411
Specialties
Radiation Oncology
Education
Medical school:

Degrees

  • 1972, M.D., New York Medical College, Valhalla, NY
  • 1968, B.A., Brooklyn College, Brooklyn, NY

Fellowship

  • 1976–1977, Clinical Fellow, Radiation Oncology, Joint Center for Radiation Therapy, Boston, MA
  • 1975–1976, Research Fellow, Radiation Oncology, Joint Center for Radiation Therapy, Boston, MA
  • 1973–1975, Clinical Fellow, Radiation Oncology, Harvard Medical School, Boston, MA

Residency

  • 1975–1976, Chief Resident, Radiation Oncology, Joint Center for Radiation Oncology, Boston, MA
  • 1973–1975, Resident, Radiation Oncology, Joint Center for Radiation Oncology, Boston, MA

Internship

  • 1972–1973, Medical Intern, Metropolitan Hospital, New York, NY

Professional Experience

  • 2018–present, Senior Medical Director, Radiation Community and Assistant Clinical Professor, Department of Radiation Oncology, City of Hope®, Duarte, CA
  • 2006–2020, Radiation Oncologist, The Center for Radiation Therapy of Beverly Hills, Beverly Hills, CA
  • 2002–2018, Co-founder and Chief Medical Officer, Vantage Oncology Inc., Manhattan Beach, CA
  • 1995–1999, Co-founder, SalicNet Managed Care Program
  • 1993–1999, Corporate Director, Radiation Oncology, Salick Health Care, Los Angeles, CA
  • 1983–2018, Founder and Chief Executive Officer, Valley Radiotherapy Associates Medical Group Inc., Manhattan Beach, CA
  • 1983–1997, Director, Radiation Oncology, Providence St. Joseph Medical Center, Burbank, CA
  • 1979–1983, Director, Radiation Oncology, Beth Israel Hospital, Boston, MA
Academic Appointments
  • Senior Medical Director, Radiation Community
  • Assistant Clinical Professor, Department of Radiation Oncology
About Me

“From our very first meeting, Dr. Botnick put my mind at ease while discussing my treatment.” 

For more than 40 years, Leslie Botnick, M.D., has cared for patients and advanced the field of cancer treatment. He played a key role in developing the approach of treating many breast cancer patients with lumpectomy plus radiation and is also known for his work in stem cell research and studying the long-term effects of chemotherapy on bone marrow. 

Dr. Botnick trained at New York Medical College and Harvard and went on to build a distinguished career at leading institutions in Boston and Southern California. Recognized as one of the “Best Doctors in America,” he is highly respected for both his clinical expertise and his ability to explain complex information in a way patients can understand. He serves patients at City of Hope® in Sherman Oaks.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Apr 26, 2026
5.0
"Very good experience."
Apr 26, 2026
5.0
"I will recommend it to all my friends."
Apr 24, 2026
5.0
"All good thank you"
Apr 24, 2026
5.0
"All good thank you"
Feb 18, 2026
5.0
"All good."
Feb 18, 2026
5.0
"Everything good! From the moment I stepped in the door."
Feb 5, 2026
5.0
"Dr. Botnick is outstanding. I feel very comfortable having my care in his hands."
Dec 31, 2025
5.0
"Again everyone who I encountered was most professional and courteous and extended themselves for me"
Dec 31, 2025
5.0
"Yes Dr Botnick is very professional and thorough in the way he conducts his information and diagnosis"
Dec 3, 2025
5.0
"I highly recommend City of Hope"
Dec 3, 2025
5.0
"[...] I highly recommend City of Hope"
Oct 31, 2025
5.0
"Very good experience"
Sep 28, 2025
5.0
"Amazing"
Sep 28, 2025
5.0
"Very good"
Jul 31, 2025
5.0
"Good"
Jul 31, 2025
5.0
"Good"
Jul 19, 2025
5.0
"All good"
Jul 19, 2025
5.0
"I would say very good"