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Leo David Wang,

M.D., Ph.D.

Pediatric Hematologist-Oncologist

Biography photo
Location
City of Hope Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Hematologic Oncology
Pediatric Hematology Oncology
Education
Medical school:
Degrees
  • B.S., Molecular Biophysics and Biochemistry, Yale University, New Haven, CT

  • Ph.D., University of Chicago Committee on Immunology (Marcus Clark, advisor), University of Chicago, Chicago, IL

  • M.D., University of Chicago Pritzker School of Medicine, University of Chicago, Chicago, IL

Fellowship
  • Pediatric Hematology/ Oncology/Stem Cell Transplant, Dana Farber/Children’s Hospital Cancer Center, Boston, MA

  • Postdoctoral Fellow, Amy Wagers, PI, Joslin Diabetes Center and Harvard Stem Cell Institute

Residency
  • Pediatrics, Children’s Hospital of Philadelphia

Internship
  • Pediatrics, Children’s Hospital of Philadelphia, PA

Professional Experience
  • 2023-Present, Program Director, City of Hope Alpha Stem Cell Clinic, City of Hope, Duarte, CA

  • 2023-present, Associate Professor, Pediatrics and Immuno-Oncology, City of Hope, Duarte, CA

  • 2016-2023, Assistant Clinical Professor, Department of Immuno-Oncology and Department of Pediatrics, City of Hope, Duarte, CA

  • 2011-2016, Instructor in Pediatrics, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, MA

Academic Appointments
  • Associate Professor, Department of Immuno-Oncology
  • Associate Professor, Department of Pediatrics
  • Director, City of Hope Alpha Clinic
  • Director, Clinical Gene Therapy Program
About Me

Leo Wang, M.D., Ph.D, is a pediatric hematologist-oncologist at City of Hope® Cancer Center Duarte, where he also serves as director of both the City of Hope Alpha Clinic and the Clinical Gene Therapy Program. 

A nationally recognized expert in pediatric hematology-oncology, Dr. Wang leads a research lab dedicated to leveraging the immune system to combat childhood cancers. His team specializes in cellular engineering, modifying the body’s own immune cells to target and destroy cancer cells or to adapt to the ways in which some tumors may become resistant to conventional treatments. Dr. Wang also oversees clinical trials that use these advanced cellular therapies to treat pediatric brain tumors and other aggressive cancers. 

In addition to his research work, Dr. Wang serves as the director of City of Hope’s Alpha Clinic, which is part of a nine-site network across California supported by the California Institute for Regenerative Medicine. This initiative is designed to improve patient access to stem cell and regenerative medicine clinical trials. In this role, Dr. Wang collaborates with colleagues at City of Hope and throughout the state to develop a strong, long-term clinical trial infrastructure, ensuring that leading-edge care is available to people across California. 

Dr. Wang received his bachelor’s degree in molecular biophysics and biochemistry from Yale University, then went on to earn both his medical degree and a Ph.D. from the University of Chicago. He completed his internship and residency at the Children’s Hospital of Philadelphia, followed by a fellowship in pediatric hematology/oncology and stem cell transplantation at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. During this time, he also conducted postdoctoral research in Dr. Amy Wagers’ lab at the Harvard Stem Cell Institute.

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