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Jessica Cheng,

M.D.

Physiatrist

4.9 (41 Ratings)
Biography photo
Location
City of Hope Orange County Lennar Foundation Cancer Center
1000 Five Point
Irvine, CA 92618
City of Hope Sand Canyon
16300 Sand Canyon Avenue, Suite 207
Irvine, CA 92618
Specialties
Supportive Care Medicine
Education
Medical school:

2017, Doctor of Medicine, Boston University School of Medicine, Boston, Massachusetts

Residency:

2018–2021, Physical Medicine and Rehabilitation, Loma Linda University Health, Loma Linda, California

Academic Appointments
  • Assistant Clinical Professor, Department of Supportive Care Medicine
About Me

Jessica Cheng, M.D., is a physiatrist at City of Hope® Orange County Lennar Foundation Cancer Center. Dr. Cheng is one of only a handful of specialists nationwide – and the only one in Orange County – trained in cancer rehabilitation medicine, a field that focuses on helping people with cancer improve their physical function and overall wellbeing. Dr. Cheng works closely with patients from the time they receive a cancer diagnosis to help them manage the physical, neurological and emotional issues related to cancer or its treatments. 

At City of Hope, Dr. Cheng builds rehabilitation plans that are tailored to each person’s unique physical, mental and emotional needs. These plans may include physical and occupational therapy, exercise programs, non-opioid pain treatments, joint and muscle injections, braces or supportive devices. She partners with cancer care teams, other medical specialists and the Department of Supportive Care to ensure that each patient’s care meets their unique requirements. 

Dr. Cheng completed medical school at Boston University, followed by an internal medicine internship and a physical medicine and rehabilitation residency at Loma Linda University Health in California. She also completed a cancer rehabilitation fellowship at MD Anderson Cancer Center in Houston, Texas, and now helps lead national efforts to expand research and education in this growing field.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Apr 25, 2026
5.0
"Excellent experience"
Mar 25, 2026
5.0
"Dr Cheng was incredibly generous with her time and so very supportive of my extremely challenging journey to find answers to extreme dysphagia present solutions going forward"
Mar 14, 2026
4.0
"CoH is beyond amazing for the wrap-around care they provide."
Mar 14, 2026
4.0
"Dr Cheng gave me a full overview of recommended exercise, nutrition and mental health/spiritual work to aid in healing from my cancer. It was overwhelming and felt impossible given my current treatment regimen. Althoughninexplained this, she still insisted that I try and do a lot more than I'm currently able to do really. I think it's a good guide aspirationally, and will be very helpful after I am done with my radiation treatments and start to eat more solid foods and am less exhausted."
Feb 11, 2026
5.0
"Pleased with my care at COH, really grateful for my Doctors and all the staff there"
Feb 11, 2026
5.0
"Dr Cheng was excellent . She took the time to understand my condition and provided good assistance not only for my physical condition but my mental approach . She was very positive and encouraging"
Jan 9, 2026
5.0
"Dr Cheng spent a lot of time with me"
Dec 31, 2025
5.0
"Dr. Cheng is 10/10"
Nov 15, 2025
5.0
"Dr. Jessica extremely knowledgeable and helpful. Listened and solicited all my post treatment issues. Had solid advice for all. Did extensive evaluation always explaining the background and intent. Much appreciated. Very good interaction."
Sep 30, 2025
5.0
"Dr Cheng was exceptionally competent, diligent, caring, thorough...really excellent !"