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Jennifer Tseng,

M.D., F.A.C.S.

Surgical Oncologist

Biography photo
Location
City of Hope Orange County Lennar Foundation Cancer Center
1000 Five Point
Irvine, CA 92618
Specialties
Breast Surgical Oncology
Education
Medical school:
Board Certifications
Degrees
  • 2004, Bachelor of Arts, History and Molecular and Cell Biology (Double Major), University of California Berkeley, CA
  • 2009, Doctor of Medicine, University of California Davis, Sacramento, CA
     
Fellowships
  • 2017-2018, Medical Education Research, Innovation, Teaching and Scholarship Fellowship, University of Chicago, Chicago, IL
  • 2015-2017, Complex General Surgical Oncology, University of Chicago, Chicago, IL
  • 2015-2016, Clinical Medical Ethics, The MacLean Center for Clinical Medical Ethics, Chicago, IL
  • 2012-2013, Clinical Immunotherapy, National Cancer Institute, Bethesda, MD
Residency
  • 2010-2015: General Surgery, Oregon Health and Science University, Portland, OR

Internship
  • 2009-2010, General Surgery, Oregon Health and Science University, Portland, OR
Professional Experience
  • 2022-present, Associate Clinical Professor, Division of Breast Surgery, Department of Surgery, City of Hope Orange County

  • 2017-2022, Assistant Professor, Department of Surgery (Section of General Surgery), University of Chicago Medicine, Chicago, IL
Academic Appointments
  • Medical Director, Division of Breast Surgery, City of Hope Orange County
  • Associate Clinical Professor, Division of Breast Surgery, Department of Surgery
About Me

Jennifer Tseng, M.D., F.A.C.S., is a surgical oncologist who specializes in breast cancer surgery and the medical director of breast surgery for City of Hope® Orange County Lennar Foundation Cancer Center. A strong supporter of shared doctor-patient decision-making, Dr. Tseng believes the best care comes when patients are fully informed and involved in every step of their cancer journey. Known for her careful attention to detail, Dr. Tseng is deeply committed to helping her patients achieve the best possible outcomes through thoughtful surgical planning and compassionate care. 

An Orange County native, Dr. Tseng earned her medical degree from the University of California, Davis. She then completed a general surgery training at Oregon Health & Science University in Portland, followed by an advanced fellowship in clinical immunotherapy at the National Cancer Institute and another in complex surgical oncology at the University of Chicago. She also pursued fellowships specializing in medical education and clinical ethics at the MacLean Center at the University of Chicago. 

At City of Hope Orange County, Dr. Tseng serves as medical director of breast surgery, where she offers leading-edge options for breast and soft tissue cancers, including oncoplastic techniques, nipple-sparing mastectomies with immediate reconstruction and access to clinical trials. Her research has appeared in publications including the Journal of Clinical Oncology and Annals of Surgery, and she has contributed to more than 100 peer-reviewed scientific publications. 

Before joining City of Hope, Dr. Tseng was a faculty member at the University of Chicago, where she received her department’s Excellence in Teaching Award. She is also active in national professional associations such as the Society of Surgical Oncology, the American Society of Clinical Oncology and the American Society of Breast Surgeons. 

Outside of work, Dr. Tseng enjoys spending time with her family and discovering the local food and arts scene.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Apr 30, 2026
5.0
"I started my testing at [...] but after visiting the City of Hope I decided this hospital was a better fit for me."
Apr 28, 2026
5.0
"I am truly grateful to have Dr. JENNIFER TSENG, as my physician. Her professionalism, compassion, and dedication to her patients are deeply appreciated. I feel very fortunate to be under her care."
Apr 17, 2026
5.0
"I would 100% recommend this provider. She was amazing from start to finish in my care."
Apr 17, 2026
5.0
"I would most definitely recommend this practice. I have had such a professional experience, from walking to the front desk, to leaving. Everyone is so caring and polite."
Apr 10, 2026
5.0
"Yes I was highly impressed with COH staff and especially my surgeons!"
Feb 13, 2026
5.0
"Dr. TSENG IS KNOWLEDGABLE, LOVELY DOCTOR. SO LUCKY TO HAVE HER AS MY SURGEON."
Jan 28, 2026
5.0
"I had a very good experience, it was my first time meeting the Doctor. I felt very comfortable and at ease."
Jan 27, 2026
5.0
"It seems that all concerns with my health have always been addressed and explained so that I have a good understanding."
Jan 21, 2026
5.0
"So good and good that we passed recommending them."
Jan 21, 2026
5.0
"My doctor, the hospital and the staff are so good that we already recommend them and talked about our experience, thank you."
Dec 2, 2025
5.0
"Dr Tseng was wonderful !!"
Nov 28, 2025
5.0
"Dr. Tseng is an outstanding doctor. She was friendly and polite and took the time to explain everything clearly and thoroughly. She answered all of my questions in a straightforward and easy-to-understand manner."
Nov 11, 2025
5.0
"Dr. Tseng was thorough and took time for questions between sections of information. She was patient and nurturing. My husband was particularly grateful for when I became emotional that Dr. Tseng didn't try to stop me or quiet me. She was in the moment with me."
Nov 7, 2025
5.0
"Every single doctor, nurse, receptionist, scheduler is outstanding at this location!!"
Nov 7, 2025
5.0
"City of Hope provides the highest quality of care for any/all cancer patients. I recommended them to everyone!"
Oct 14, 2025
5.0
"Out of 5 stars I give COH 10 stars!"
Oct 14, 2025
5.0
"Dr J. Tseng gave such great care! From the first time I met her, she was alwys very friendly, professional, supportive, and answered my many questions. With my cancer type, she was pretty optimistic that with surgery, I could become cancer free. That was such hopeful news and something I never expected. After surgery and upon report from pathology, she called me with the best news ever. I was now cancer free! It was the best news! I believe she also enjoyed sharing it as much as I enjoyed hearing it. My many thanks and appreciation to Dr J. Tseng and all the staff at COH, Irvine for such great care. It is with my hope that many more patients will receive good news as well."
Sep 24, 2025
5.0
"Very impressed w/ Dr Tseng, she was very present in our conversation, explained things very well and I felt heard and included in the decision making."
Sep 11, 2025
5.0
"Very good"
Sep 11, 2025
5.0
"Very good"
Sep 9, 2025
5.0
"I had a very good experience and feel confident in Dr. Tseng's care."
Aug 31, 2025
5.0
"Love my doctor. Very compassionate and understanding"
Aug 19, 2025
5.0
"My experience was awesome. Wonderful staff."
Aug 14, 2025
5.0
"I was very, very impressed with my visit [...]"
Jul 26, 2025
5.0
"Most amazing, caring doctor you could ask for"
Jul 12, 2025
4.7
"Dr Jennifer Tseng was so informative, helpful, and caring! My first appointment with City of Hope I walked in very scared and stressed and she gave me lots of hope and comfort regarding treatment and outcome for my condition."
Jul 8, 2025
5.0
"My sole criticism is with the lack of urgency to schedule my surgery."
Jul 8, 2025
5.0
"Very good"
Jul 8, 2025
5.0
"Very good"