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Jeffrey Y.C. Wong,

M.D.

Radiation Oncologist

4.9 (69 Ratings)
Biography photo
Location
City of Hope Comprehensive Cancer Center - Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Radiation Oncology
Genitourinary Oncology
Education
Medical school:

1981,M.D., Medicine, Johns Hopkins University, Baltimore, Maryland, Medicine

Residency:

1982-1985, Radiation Oncology, University of California San Francisco, San Francisco, California

Academic Appointments
  • Professor, Department of Radiation Oncology
  • Professor, Department of Immunology & Theranostics
  • Co-director, Center for Theranostic Studies
About Me

Jeffrey Y.C. Wong, M.D., is a professor of radiation oncology, professor of immunology and theranostics and the co-director of City of Hope® Duarte’s groundbreaking Center for Theranostic Studies. 

With more than 25 years of experience at City of Hope alone, Dr. Wong has been instrumental in helping the institute’s Department of Radiation Oncology become one of the country’s most advanced, offering leading-edge treatments ranging from image-guided and intensity-modulated radiation therapy to TomoTherapy, CT simulation and advanced techniques like radioimmunotherapy and brachytherapy. As co-director of the Center for Theranostic Studies, Dr. Wong and his team work on advanced techniques that help physicians locate and treat cancer cells and tumors at the same time—an approach that’s changing how cancer care is delivered.

In his role as a radiation oncologist and physician-scientist, Dr. Wong focuses on developing new, more precise ways to deliver radiation treatment. He has helped create a targeted form of bone marrow radiation, treating the first patient in 2005 through a collaboration between the radiation team and bone marrow transplant specialists. He and his team have also pioneered a new method for total body irradiation (TBI) using image-guided and intensity-modulated radiation. This technique, called total marrow irradiation (TMI) or total marrow and lymphoid irradiation (TMLI), allows doctors to better target cancer while protecting healthy organs. City of Hope was the first in the world to use this approach in patients, and Dr. Wong’s team has shared their work with centers in Asia and Europe. 

As co-director of the Center for Theranostic Studies, Dr. Wong continues to lead efforts in developing targeted treatments using radiopharmaceuticals—special drugs that carry radiation directly to cancer cells. He has led or co-led more than 20 clinical trials using these treatments for cancers of the colon, stomach, breast, lung and thyroid. His work helps bring promising new therapies from the lab directly to patients, offering more options and hope for the future.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Jan 25, 2026
4.7
"The information, while extremely helpful, was a lot and a bit overwhelming. However my visit was 100% great and helpful"
Jan 22, 2026
5.0
"[...] Of all of the physicians In California the absolute best that I could find who could deal with my cancer was Dr Jeffrey Wong (I literally read dozens of CV's). During the entire treatment cycle Dr Wong was ever present. He would respond to my questions completely. I was exceeding pleased with Dr. Wong."
Jan 16, 2026
5.0
"Good"
Jan 16, 2026
5.0
"Good"
Jan 3, 2026
5.0
"Excellent discussion and care"
Jan 3, 2026
5.0
"Dr. Wong is simply the best."
Nov 23, 2025
5.0
"Good"
Nov 23, 2025
5.0
"Very good"
Sep 29, 2025
5.0
"Everyone was very helpful"
Sep 29, 2025
5.0
"Provider was very helpful"
Sep 27, 2025
5.0
"Empathetic. Patient in explanation. Kind. Not in a hurry to other appointments."
Sep 27, 2025
5.0
"City of Hope earns my highest rating of all hospital facilities I've been to. Superb in every respect."
Sep 2, 2025
5.0
"Very Very Good.#1"
Aug 29, 2025
4.3
"I have already recommended a few friends to your hospital"
Aug 25, 2025
5.0
"Excellent"
Aug 25, 2025
5.0
"DR and staff are very professionals"
Aug 19, 2025
5.0
"Dr. Wong is the best."
Aug 18, 2025
5.0
"Good"
Aug 18, 2025
5.0
"Good"
Aug 4, 2025
4.4
"Very well"
Jul 29, 2025
5.0
"Have recommended you frequently"
Jul 29, 2025
5.0
"[...] He is magnificent as a physician as well as being a fantastic gentleman."