M.D.
Professor and Chair, Department of Hematologic Malignancies Translational Science
A world-renowned expert in his field, Guido Marcucci, M.D., is the chair of the Department of Hematologic Malignancies Research at City of Hope® Cancer Center Duarte. He is also director of the Gehr Family Center for Leukemia Research, chief of the leukemia program and vice chair and professor in the Department of Hematology and Hematopoietic Cell Transplantation.
From early on in his career, Dr. Marcucci has been driven by a desire to understand what triggers the onset of cancer. He views leukemia—particularly acute myeloid leukemia (AML)—as an ideal model to explore the underlying mechanisms of cancer development and, as such, he has made AML a central focus of his groundbreaking research. His commitment to unlocking the complexities of this disease has defined much of his professional journey. In his current roles at City of Hope, Dr. Marcucci plays an instrumental role in expanding the institution’s legacy of excellence in leukemia research and treatment.
Prior to joining City of Hope, Dr. Marcucci served as a professor in multiple disciplines at The Ohio State University, including internal medicine, molecular virology, immunology, medical genetics, and pharmaceutics. He is an internationally recognized expert in leukemia who has delivered keynote lectures across the globe and published more than 500 scientific articles. His work—backed by numerous National Cancer Institute grants—focuses on understanding the biology of AML, improving therapeutic strategies and refining prognostic tools. He also contributes to the field as a member of editorial boards for leading journals, including Blood and the Journal of Clinical Oncology.
Dr. Marcucci earned his medical degree at the Catholic University of the Sacred Heart in his native Italy, where he also completed a residency in dermatology and a fellowship in internal medicine. After moving to the United States, he pursued an internship and residency in internal medicine at the State University of New York in Buffalo, followed by a fellowship in medical oncology at Roswell Park Cancer Institute in the same city.