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Guido Marcucci,

M.D.

Professor and Chair, Department of Hematologic Malignancies Translational Science

Biography photo
Location
City of Hope Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Hematologic Oncology
Education
Medical school:
Board Certifications
  • Internal Medicine

  • Oncology

Degrees
  • 1986, M.D. Catholic University of the Sacred Heart, Rome, Italy

Fellowship
  • 1995-1997, Medical Oncology Fellowship, Dept. of Medicine, Roswell Park Cancer Institute, Buffalo, NY

  • 1990, Internal Medicine Fellowship, Regione Lazio, Italy

Residency
  • 1990-1993,  Internship and Residency in Internal Medicine, State University of New York, Buffalo, N.Y.

  • 1986-1989 Residency in Dermatology, Dept. of Dermatology, Catholic University of the Sacred Heart, Rome, Italy

Internship
  • 1990-1993, Internship and Residency in Internal Medicine, State University of New York, Buffalo, NY

Professional Experience
  • 2020-present, Chief, Division of Leukemia

  • 2017-2020, Chair and Professor, Department of Hematologic Malignancies Translational Science, Beckman Research Institute of City of Hope, Duarte, CA

  • 2014-present, Associate Director of Basic Research, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA

  • 2014-present, Professor, Hematology & Hematopoietic Cell Transplantation, City of Hope, Duarte, CA

  • 2014– present, Director, Hematopoietic Tissue Biorepository (HTB)

  • 2009-2014, Professor of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, and Pharmaceutics Division Hematology, Comprehensive Cancer Center and The Ohio State University, Columbus, OH

Academic Appointments
  • Vice Chair, Department of Hematology
  • Chief, Division of Leukemia
  • Chair and Professor, Department of Hematologic Malignancies Translational Science
  • Director, Gehr Family Center for Leukemia Research
  • Professor, Department of Hematology & Hematopoietic Cell Transplantation
  • Director, Hematopoietic Tissue Biorepository (HTB)
About Me

A world-renowned expert in his field, Guido Marcucci, M.D., is the chair of the Department of Hematologic Malignancies Research at City of Hope® Cancer Center Duarte. He is also director of the Gehr Family Center for Leukemia Research, chief of the leukemia program and vice chair and professor in the Department of Hematology and Hematopoietic Cell Transplantation. 

From early on in his career, Dr. Marcucci has been driven by a desire to understand what triggers the onset of cancer. He views leukemia—particularly acute myeloid leukemia (AML)—as an ideal model to explore the underlying mechanisms of cancer development and, as such, he has made AML a central focus of his groundbreaking research. His commitment to unlocking the complexities of this disease has defined much of his professional journey. In his current roles at City of Hope, Dr. Marcucci plays an instrumental role in expanding the institution’s legacy of excellence in leukemia research and treatment. 

Prior to joining City of Hope, Dr. Marcucci served as a professor in multiple disciplines at The Ohio State University, including internal medicine, molecular virology, immunology, medical genetics, and pharmaceutics. He is an internationally recognized expert in leukemia who has delivered keynote lectures across the globe and published more than 500 scientific articles. His work—backed by numerous National Cancer Institute grants—focuses on understanding the biology of AML, improving therapeutic strategies and refining prognostic tools. He also contributes to the field as a member of editorial boards for leading journals, including Blood and the Journal of Clinical Oncology

Dr. Marcucci earned his medical degree at the Catholic University of the Sacred Heart in his native Italy, where he also completed a residency in dermatology and a fellowship in internal medicine. After moving to the United States, he pursued an internship and residency in internal medicine at the State University of New York in Buffalo, followed by a fellowship in medical oncology at Roswell Park Cancer Institute in the same city.

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