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Dani Castillo,

M.D.

Medical Oncologist

4.7 (105 Ratings)
Biography photo
Location
City of Hope Comprehensive Cancer Center - Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Medical Oncology
Education
Medical school:

2010, M.D., Medizinische Fakultät Heidelberg, Ruprecht-Karls-Universität Heidelberg, Germany

Residency:

2017–2020, Internal Medicine, Hackensack University Medical Center/Englewood Hackensack, New Jersey

Academic Appointments
  • Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research
About Me

Dani Castillo, M.D., is a medical oncologist at City of Hope® Cancer Center Duarte, where she focuses on conducting leading-edge research into new therapies and approaches to treating esophageal and gastric cancers. 

Dr. Castillo, who was motivated to pursue a career in medicine after a close family member was diagnosed with cancer, takes a compassionate, patient-focused approach to care that treats the patient-physician relationship as a partnership. She works closely with those diagnosed with cancer to ensure that their personal values are taken into account during treatment that they are able to make informed decisions about their care. 

After earning her medical degree at Ruprecht-Karls-Universität in Heidelberg, Germany, Dr. Castillo took on a postdoctoral research fellowship in stem cell transplantation at the University of California, San Diego. She later explored lung cancer as a research associate at the University of Southern California in Los Angeles. Her contributions to oncology have earned her accolades including the Merit Award from the American Society of Clinical Oncology in 2023 and an Abstract Achievement Award from the American Society of Hematology in 2012. When she joined City of Hope in 2023, she had already authored a dozen peer-reviewed publications, including articles featured in the Journal of Clinical Oncology and Blood. 

Outside of the professional arena, Dr. Castillo enjoys taking Zumba classes, exploring new places and watching basketball. She is fluent in English, Mandarin, Spanish and German.

Patient reviews
The patient ratings and comments on this page are obtained from an external Press Ganey® outpatient survey provided to all eligible City of Hope patients within one to two weeks of their treatment occurrence. Raw data from the answers to the survey questions about our physicians are calculated by Press Ganey into a one- to five- star rating. In the spirit of transparency, all patient comments are posted as written by the patient, whether they are positive or negative. We only exclude comments if they are deemed to be slanderous or libelous, contain profanity or vulgar language, or do not relate to the patient's experience with the doctor involved. As a result, the comments are the views and opinions of the patients surveyed and are not endorsed by, and may not necessarily reflect the opinion of, City of Hope.
Mar 21, 2026
5.0
"Everything went well"
Mar 21, 2026
5.0
"No complaints from me"
Mar 13, 2026
4.9
"She took time to explain my current plan and options that City of Hope can provide."
Dec 21, 2025
5.0
"I would highly recommend Dr. Dani Castillo's practice."
Dec 21, 2025
5.0
"Dr. Dani Castillo is an amazingly caring and thorough doctor. This was just a consultation, but I would highly recommend her."
Nov 20, 2025
5.0
"Good everything"
Nov 20, 2025
5.0
"Good everything"
Nov 12, 2025
4.6
"Incredibly responsive and kind team members, physicians, surgeons, etc. I felt seen and cared for from my first call to inquire about a second opinion through today first cycle of chemo almost complete."
Nov 12, 2025
4.6
"I asked questions more than once and really wanted to understand the details of the treatment plan. She was reassuring and spent time with me on a telemedicine visit to answer all my questions."
Nov 6, 2025
5.0
"Good"
Nov 6, 2025
5.0
"Good"
Aug 21, 2025
5.0
"Doctor was very positive, welcoming, well prepared"
Aug 21, 2025
5.0
"I appreciate the good service and look forward to working with you"
Aug 15, 2025
5.0
"Already have told friends that have loved ones with cancer about it. They are questioning me about City of Hope as soon as they find out that I go here. I encourage them to check you out."
Aug 8, 2025
5.0
"Outstanding team"
Aug 7, 2025
5.0
"Excellent!"
Aug 7, 2025
5.0
"Of the highest order!"
Jul 31, 2025
5.0
"Dr. Castillo is the finest doctor I have ever had in my life"
Jul 18, 2025
5.0
"Amazing Doctor"
Jun 20, 2025
5.0
"Dr Dani Castillo is an amazing caring compassionate and astute physician!"
Jun 6, 2025
3.8
"Following visit much confusion re providers recommendation re changing chemo at [...] - I was highly confused."