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6 Clinical Trials

     

Accepting new patients

 

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clinicaltrials.gov

The purpose of this study is to determine if the study drug talazoparib (also called BMN 673) is safe when given as a breast cancer treatment and to evaluate how cancer responds to it.

     

Accepting new patients

 

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clinicaltrials.gov

This is an open-label, three-part, multiple-dose study to evaluate safety, tolerability and efficacy of U3-1402 in patients with HER3-positive metastatic breast cancer.

     

Accepting new patients

 

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clinicaltrials.gov

The purpose of this study is to test study treatments that combine an investigational drug (tucatinib, which is also known as ONT-380) (the “study drug”) with two approved drugs (capecitabine and trastuzumab) in participants with advanced breast cancer to find out what effects, good or bad, it may have on the participants and their disease.

     

Accepting new patients

 

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clinicaltrials.gov

The purpose of this study is to determine which treatment regimen is better (margetuximab with standard chemotherapy versus trastuzumab with standard chemotherapy). Survival, tumor size, side effects and quality of life for the two treatments will be compared.

This study will test whether participants with metastatic (having spread to distant organs beyond the breast or close by lymph nodes) or locally-advanced (cancer that hasn’t spread but cannot be cured by surgery) HER2-positive breast cancer that has worsened following standard treatments or lines of therapy will benefit from treatment with standard chemotherapy plus margetuximab compared to standard chemotherapy plus trastuzumab (also called Herceptin®).

     

Accepting new patients

 

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clinicaltrials.gov

This is a multi-national, multi-center, randomized, open-label, parallel group phase III study.

     

Accepting new patients

 

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clinicaltrials.gov

The main objective of the trial is to assess the anti-tumor activity of xentuzumab in combination with everolimus and exemestane over everolimus and exemestane in post-menopausal patients with HR+/ HER2- advanced or metastatic breast cancer and non-visceral disease.