Cincinnati Childrens Hospital

Cincinnati Children's

Fighting the Toughest and Most Complex Cancers

Families travel from across the world to Cincinnati Children’s for cancer care because we’re experts in treating and curing the toughest, most treatment-resistant cancer. Our team integrates patient care and scientific discovery. This approach enables us to drive breakthroughs in medicine, develop new therapies, manage the most complex cancer diagnoses and be a top-ranked program in the nation.

But the most important thing we offer is hope. Our expertise and approach give hope and healing to children and their families when they need it the most.

Comprehensive, Specialized Cancer Care

The Cincinnati Children’s cancer program is built on team innovation and provides multidisciplinary, personalized treatment using the latest technology. We also specialize in meeting the unique care needs of each patient and family. Our team delivers some of the most advanced, groundbreaking therapies in the world, which are often only available here.

  • We develop new treatments for even the most difficult-to-treat cancers using “team science” that integrates our clinical and research laboratory teams. Research from our center led to the recent pediatric Food and Drug Administration (FDA) approvals of the new drugs Vyxeos for acute myeloid leukemia and selumetinib for patients with inoperable neurofibromatosis tumors.
  • We were pioneers in the use of “next generation sequencing” to understand the genetic wiring of relapsed cancers and leukemias that have escaped traditional therapies. Then we tailor treatments to those cancers with new targeted drugs and immune therapies.
  • Chimeric antigen receptor (CAR) T-cell therapy uses a patient’s own immune system to kill aggressive and treatment-resistant cancers. Our program is one of the most experienced in the country with many options for leukemia and lymphoma, giving more children the opportunity to benefit from this lifesaving therapy.
  • Our Proton Therapy Center delivers the most advanced form of radiation therapy available. This technology destroys cancer cells while minimizing damage to surrounding healthy tissues and organs, and has fewer side effects to the brain.
  • We’re leading the field in advances in radiation therapy with the world’s first clinical trial of ultra-high-dose rate “FLASH” proton therapy. FLASH is a new technology that may reduce potential side effects and allow for an increased dose to better treat and potentially cure aggressive brain tumors, sarcomas, lymphomas and other cancers.
  • Our researchers and clinicians are developing new uses of T-cell therapies to treat and prevent deadly viral infections in immunocompromised cancer patients.
Cincinnati Children's

Hope begins here.

Advances in cancer care allow most children to respond to traditional therapies. But when your child needs specialized care, we deliver advanced treatments and hope.

Our Programs and Services

Our team provides specialized care and treatments for all forms of childhood cancers through advanced treatments and multidisciplinary care. Our leaders spearhead international studies and develop treatments that are used around the world.

The Bone Marrow Transplant Program has performed more than 2,300 transplants. Our team helped develop bone marrow transplant strategies that are now the standard of care across the globe.

The Brain Tumor Center is a world-renowned destination for children with rare and treatment-resistant (refractory) brain tumors. Each year, the team sees hundreds of new patients, many of whom travel internationally to Cincinnati for clinical trials and other treatment plans available only at Cincinnati Children’s.

The Kidney Tumors Program is led by international experts who offer advanced therapies and access to new anticancer research studies for children with newly diagnosed, advanced, rare and relapsed kidney cancers.

The Leukemia and Lymphoma Center is one of the nation’s largest and most technically advanced referral centers for patients with leukemia, lymphoma and related disorders. We lead in the development of new therapies for patients with high-risk and relapsed blood cancers, including next generation precision medicine with new targeted drugs, cellular and immunotherapies and novel bone marrow transplant approaches.

The Liver Tumors Program is a globally recognized center and a leader at the forefront of providing innovative surgical and medical therapies. Our experts treat patients newly diagnosed with rare liver tumors and also those in the advanced stages of disease or who require liver transplants.

The Neuroblastoma Advanced Therapies Center is run by national leaders who create new studies and approaches to target and kill neuroblastoma cells. The team provides expert, multidisciplinary care for children with newly diagnosed and relapsed or refractory neuroblastoma.

The Neurofibromatosis (NF) Program is one of the largest in the nation and helps those affected by the different types of NF through comprehensive diagnosis, treatment and research for these conditions. Our team’s research led to the first FDA approval of a therapy for children with neurofibromatosis type 1 (NF1) and inoperable plexiform neurofibromas.

The Retinoblastoma Program includes specialists in cancer, ophthalmology, neuro-interventional radiology and neurosurgery. The team uses a collaborative approach, innovative technologies and breakthrough therapies to provide care.

The Sarcoma Program is a national leader in providing advanced therapies for children with tumors of the bone and soft tissues. Some of our patients have newly diagnosed sarcomas, while others come to Cincinnati Children’s seeking novel therapies for recurrent, rare or treatment-resistant sarcomas.

Cincinnati Children's

Top-Ranked Cancer Program

Cincinnati Children’s is consistently ranked in the top 3 cancer programs by U.S. News & World Report. We’re also accredited with commendation from the American College of Surgeons Commission on Cancer. We don’t stop there. Our pediatric cancer rehabilitation program is the first in the world to be accredited by the Commission on Accreditation of Rehabilitation Facilities (CARF).

But even more important than rankings, it’s our approach that helps deliver hope and healing for children and their families. That’s why two-thirds of our patients come to Cincinnati Children’s for treatment to fight the hardest, most-complex cancers.

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Looking for a second opinion?

Cincinnati Children’s provides cancer second opinions to help families understand all available treatment options and make more informed decisions.

Fertility Preservation

Fewer than half of young cancer patients are offered fertility preservation. Our team focuses on your child’s future from the start. We believe that fertility is an important aspect of medical care for every patient, and it requires consideration even during childhood.

Our Fertility Care & Preservation Program provides the most advanced technologies, including freezing and storing eggs or ovarian tissue for later use for females, and freezing and storing testicular tissue or sperm for males. This team meets with patients whose treatment regimens place them at risk for fertility complications in the future. By educating patients and families early on about the fertility risks of their diagnosis and treatments, they can determine if fertility preservation is available and right for them. We help the patient and family to understand the strengths, limitations, successes and science behind each option.

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Helping Childhood Cancer Survivors Thrive

Thanks to modern cancer treatments, more children survive cancer than ever before. In fact, at Cincinnati Children’s we believe survivorship starts the day a child is diagnosed; every treatment plan aims to help children live with—and beyond—their cancer. That’s why our Cancer Survivorship Center provides specialized medical care and psychosocial support to childhood cancer survivors continuously and without interruption through adulthood.

Cincinnati Children’s established the program 30 years ago as one of the first of its kind in the country. The center serves children and adult survivors who range in age from 5 to more than 65 years old. It is a national leader in the development of innovative approaches to provide care, research and education to this growing population.

Cincinnati Children's