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Clinical trials

Cancer Treatment Centers of America (CTCA) is committed to bringing you new and innovative investigational cancer treatment options. One way we do this is by participating in cancer research trials and studies.

To learn more about a specific clinical trial, please follow the "Request more information" link under each trial title. For more information regarding clinical trials in general, please email the Clinical Trials team at clinicaltrials@ctca-hope.com or contact one of our Oncology Information Specialists at 888-841-9129. Oncology Information Specialists are available around the clock, 24 hours a day, 7 days a week, to discuss treatment options offered at CTCA.

We do not currently have a clinical trials for this cancer type and hospital.

Basal cell carcinoma

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

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This trial is offered at the following facilities: Western Regional Medical Center

Bile duct cancer

PIN-PHO1201 Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma

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This trial is offered at the following facilities: Southwestern Regional Medical Center,Western Regional Medical Center

Bladder cancer

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Ramucirumab plus Docetaxel Versus Placebo plus Docetaxel in Patients with Locally Advanced or Unresectable or Metastatic Urothelial Carcinoma Who Progressed on or After Platinum-Based Therapy (Eli Lilly I4T-MC-JVDC)

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This trial is offered at the following facilities: Southeastern Regional Medical Center

Breast cancer

A randomized, double-blind, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therpay for Metastatisc Triple-Negative Breast Cancer (FRIDA)

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This trial is offered at the following facilities: Southeastern Regional Medical Center

MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer

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This trial is offered at the following facilities: Midwestern Regional Medical Center,Southeastern Regional Medical Center

NEOADAPT – A phase II study of NEOADjuvant Aromatase inhibitor and Pertuzumab/Trastuzumab (NEOADAPT) without chemotherapy for women with breast cancer

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This trial is offered at the following facilities: Midwestern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients with Early-Stage HER2+ Breast Cancer Treated with Neratinib and Intensive Loperamide Prophylaxis (PUMA)

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Multistage, Phase II Study Evaluating the Safety and Efficacy of Cobimetinib in Combination with Paclitaxel as First-Line Treatment for Patients with Metastatic Triple-Negative Breast Cancer

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase 3, Randomized Study of Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of Patients with HER2+ Metastatic Breast Cancer Who Have Received Two Prior Anti-HER2 Therapies and Require Systemic Treatment (SOPHIA)

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This trial is offered at the following facilities: Western Regional Medical Center

neoMONARCH: A Phase 2 Neoadjuvant Trial Comparing the Biological Effects of 2 Weeks of Abemaciclib (LY2835219) in Combination With Anastrozole to Those of Abemaciclib Monotherapy and Anastrozole Monotherapy and Evaluating the Clinical Activity and Safety of a Subsequent 14 Weeks of Therapy With Abemaciclib in Combination With Anastrozole in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast Cancer

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

Chronic lymphocytic leukemia (CLL)

A Phase 3, Randomized, Study to Assess the Efficacy and Safety of Ublituximab in Combination With Ibrutinib Compared to Ibrutinib Alone, in Patients With Previously Treated High-Risk Chronic Lymphocytic Leukemia (CLL)

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This trial is offered at the following facilities: Southeastern Regional Medical Center

Colorectal cancer

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Gastrointestinal cancer

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

General

A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-042, an Anti-PD-1 Monoclonal Antibody, in Patients With Advanced Solid Tumors

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This trial is offered at the following facilities: Western Regional Medical Center

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

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This trial is offered at the following facilities: Western Regional Medical Center

My Pathway: An Open-Label Phase IIA Study Evaluating Trastuzumab/Pertuzumab, Erlotinib, Vemurafenib, and Vismodegib in Patients Who Have Advanced Solid Tumors with Mutations or Gene Expression Abnormalities Predictive of Response to One of These Agents

View the trial        Western Regional Medical Center: Request more information

                                Eastern Regional Medical Center: Request more information

                                Midwestern Regional Medical Center: Request more information

                               Southeastern Regional Medical Center: Request more information

This trial is offered at the following facilities: Western Regional Medical Center,Eastern Regional Medical Center,Midwestern Regional Medical Center,Southeastern Regional Medical Center

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK1/2/3, ROS1, or ALK Gene Rearrangements (Fusions) (STARTRK-2)

View the trial        Western Regional Medical Center: Request more information

                                Eastern Regional Medical Center: Request more information

                                Midwestern Regional Medical Center: Request more information

                               Southeastern Regional Medical Center: Request more information

                               Southwestern Regional Medical Center: Request more information

This trial is offered at the following facilities: Western Regional Medical Center,Eastern Regional Medical Center,Midwestern Regional Medical Center,Southeastern Regional Medical Center,Southwestern Regional Medical Center

Modular phase II study to link targeted therapy to patients with pathway activated tumors: Module 7 – Ceritinib (LDK378) for patients whose tumors have aberrations in ALK or ROS1

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This trial is offered at the following facilities: Eastern Regional Medical Center

Glioblastoma multiforme (GBM)

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

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This trial is offered at the following facilities: Western Regional Medical Center

Head and neck cancer

A Phase III Randomized Trial of MK-3475 (Pembrolizumab) versus Standard Treatment in Subjects with Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040)

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This trial is offered at the following facilities: Southwestern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

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This trial is offered at the following facilities: Midwestern Regional Medical Center

Kidney cancer

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Liver cancer

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

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This trial is offered at the following facilities: Western Regional Medical Center

Lung cancer

A Phase III, Open-label, Multicenter, Randomzed Study Evaluating the Efficacy and Safety of MPDL3208A (Anti-PDL-1 Antibody) in Combination With Carboplatin + Paclitaxel or MPDL3208A in Combination With Carboplatin + Nab-paclitaxel Versus Carboplatin + Nab-paclitaxel in Chemotherapy-naive Patients With Stage IV Squamous Non-small Cell Lung Cancer

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase I, multi-center, randomized open label study to assess the systemic exposure and safety of 450 mg ceritinib taken with a low-fat meal and 600 mg ceritinib taken with a low-fat meal as compared with that of 750 mg ceritinib taken in the fasted state in adult patients with ALK rearranged (ALK-positive) metastatic non-small cell lung cancer (NSCLC) (Novartis CLDK378A112)

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients With ALK-positive non-small cell lung cancer (NSCLC) Metastatic to the Brain and/or to Leptomeninges (Novartis CLDK378A2205/Ascend-7)

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This trial is offered at the following facilities: Southwestern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Lymphoma

A Phase 3b Randomized Study of Lenalidomide (CC-5013) Plus Rituximab Maintenance Therapy Followed by Lenalidomide Single-Agent Maintenance Versus Rituximab Maintenance in Subjects with Relapsed/Refractory Follicular, Marginal Zone or Mantle Cell Lymphoma

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This trial is offered at the following facilities: Southeastern Regional Medical Center

Phase 3 randomized, double-blind, placebo controlled, multicenter study to compare the efficacy and safety of lenalidomide (cc-5013) plus r-chop chemotherapy (r2-chop) versus placebo plus r-chop chemotherapy in subjects with previously untreated activated B-cell type diffuse large B-cell lymphoma

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This trial is offered at the following facilities: Southeastern Regional Medical Center

Non-small cell lung cancer (NSCLC)

A Phase III Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of MPDL3280A (Anti-PD-L1 Antibody) in Combination With Carboplatin + Nab-Paclitaxel for Chemotherapy-Naive Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase III, Randomized, Double-blind, Placebo-controlled, Multi-centre, International Study of MEDI4736 as Sequential Therapy in Patients with Locally Advanced, Unresectable Non-Small Cell Lung Cancer (Stage III) Who Have Not Progressed Following Definitive, Platinum-based, Concurrent Chemoradiation Therapy (PACIFIC)

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This trial is offered at the following facilities: Western Regional Medical Center

Ovarian cancer

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase II, Open-label, Single-arm, Multicenter Study to Evaluate Efficacy and Safety of Pembrolizumab Monotherapy in Subjects with Advanced Recurrent Ovarian Cancer (KEYNOTE -100)

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This trial is offered at the following facilities: Eastern Regional Medical Center

Pancreatic cancer

A Randomized, Double-blind, Placebo-controlled Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine Versus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase I/II, Two-Part, Multicenter Study to Evaluate the Safety and Efficacy of M402 in Combination with nab-Paclitaxel and Gemcitabine in Patients with Metastatic Pancreatic Cancer

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This trial is offered at the following facilities: Southeastern Regional Medical Center

Nab-Paclitaxel (abraxane®) plus gemcitabine in subjects with locally advanced pancreatic cancer (lapc): An international, open-label, multi-center, phase 2 study (lapact

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

View the trial      Request more information

This trial is offered at the following facilities: Western Regional Medical Center

Small cell lung cancer (SCLC)

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Soft tissue sarcoma

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Squamous cell carcinoma

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

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This trial is offered at the following facilities: Western Regional Medical Center

Uterine cancer

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

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This trial is offered at the following facilities: Western Regional Medical Center