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Clinical trials

Cancer Treatment Centers of America (CTCA) is committed to bringing you new and innovative investigational cancer treatment options. One way we do this is by participating in cancer research trials and studies.

To learn more about a specific clinical trial, please follow the "Request more information" link under each trial title. For more information regarding clinical trials in general, please email the Clinical Trials team at clinicaltrials@ctca-hope.com or contact one of our Oncology Information Specialists at 888-841-9129. Oncology Information Specialists are available around the clock, 24 hours a day, 7 days a week, to discuss treatment options offered at CTCA.

We do not currently have a clinical trials for this cancer type and hospital.

Bile duct cancer

PIN-PHO1201 Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma

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This trial is offered at the following facilities: Southwestern Regional Medical Center

Breast cancer

L-glutamine Supplementation to Alleviate Symptoms of Taxane-Induced Neuropathy in Patients with Breast Cancer

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This trial is offered at the following facilities: Eastern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase 3, Open-Label, Randomized, Parallel, 2-Arm, Multi-Center Study of BMN 673 versus Physician’s Choice in Germline BRCA Mutation Subjects with Locally Advanced and/or Metastatic Breast Cancer, Who Have Received No More than 2 Prior Chemotherapy Regimens for Metastatic Disease

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This trial is offered at the following facilities: Eastern Regional Medical Center

A Randomized Multicenter Pivotal Study of CDX-011 (CR011-vcMMAE) in Patients with Metastatic, GPNMB Over-Expressing, Triple-Negative Breast Cancer.

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This trial is offered at the following facilities: Midwestern Regional Medical Center

A Randomized, Phase 2 Study of the Efficacy and Tolerability of Veliparib in Combination with Temozolomide or Veliparib in Combination with Carboplatin and Paclitaxel Versus Placebo Plus Carboplatin and Paclitaxel in Subjects with BRCA1 or BRCA2 Mutation and Metastatic Breast Cancer

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This trial is offered at the following facilities: Midwestern Regional Medical Center

PUMA-NER-1301: A Study of Neratinib plus Capecitabine vs. lapatinib plus Capecitabine in patients with HER2+ metastatic breast cancer who have received two or more prior HER2 directed regimens in the metastatic setting

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This trial is offered at the following facilities: Midwestern Regional Medical Center

Meso BioMatrix Acellular Peritoneum Matrix Breast Reconstruction Feasibility Trial

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This trial is offered at the following facilities: Eastern Regional Medical Center

Phase Ib/II study of Hydroxychloroquine in Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Hormonal therapy (Anti-Autophagy for Breast Cancer, ABC 01 study)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase 3 Randomized, Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the PARP Inhibitor Veliparib (ABT-888) in HER2-NegativeMetastatic or Locally Advanced Unresectable BRCA-Associated Breast Cancer

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This trial is offered at the following facilities: Midwestern Regional Medical Center

A Phase I/II Study Evaluating the Maximum Tolerated Dose, Bioequivalence/Pharmacokinetics, Safety and Efficacy of Hyperthermia and Thermodox® (Lyso-Thermosensitive Liposomal Doxirubicin) in Patients with Local-Regional Recurrent Breast Cancer

This trial is offered at the following facilities: Southwestern Regional Medical Center

Identification And Analysis Of Families With Genetic Susceptibility To Cancer

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This trial is offered at the following facilities: Eastern Regional Medical Center

A Pilot Study of Short-term Fasting on Neoadjuvant Chemotherapy in Patients with Newly Diagnosed Breast Cancer (STEFNE Study)

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This trial is offered at the following facilities: Western Regional Medical Center

Metronomic Capecitabine with Digoxin for Metastatic Breast Cancer Progressing After Anthracycline and Taxane Treatment

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase II, single arm study of the use of steroid-based mouthwash to prevent stomatitis in postmenopausal women with advanced or metastatic hormone receptor positive breast cancer being treated with everolimus plus exemestane

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This trial is offered at the following facilities: Southeastern Regional Medical Center

Neoadjuvant Hormonal Therapy Combined with Chemoimmunotherapy (Taxotere, Trastuzumab and Pertuzumab) in Patients with HER2-positive and ER-Positive Breast Cancer (NeoHTTP study)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

Colorectal cancer

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Endometrial cancer

An Open-Label, Randomized, Multi-Center, Prospective Study of the Instillation Technique Using The Modified Intra- Uterine Manipulator Catheter With Methylene Blue, Isosulfan Blue or Indocyanine Green Dyes, Compared to Cervical Injection, For Sentinel Lymph Node Detection in Endometrial Carcinoma

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This trial is offered at the following facilities: Southeastern Regional Medical Center,Southwestern Regional Medical Center

Gastrointestinal cancer

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

General

A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

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This trial is offered at the following facilities: Southwestern Regional Medical Center

Modular phase II study to link targeted therapy to patients with pathway activated tumors: Module 8 – LEE011 for patients with CDK4/6 pathway activated tumors

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas

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This trial is offered at the following facilities: Western Regional Medical Center

Compassionate Use of Omegaven in the Treatment of Parenteral Nutrition Induced Hepatic Injury

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This trial is offered at the following facilities: Midwestern Regional Medical Center

A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0010718C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications

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This trial is offered at the following facilities: Western Regional Medical Center

My Pathway: An Open-Label Phase IIA Study Evaluating Trastuzumab/Pertuzumab, Erlotinib, Vemurafenib, and Vismodegib in Patients Who Have Advanced Solid Tumors with Mutations or Gene Expression Abnormalities Predictive of Response to One of These Agents

View the trial        Western Regional Medical Center: Request more information

                                Eastern Regional Medical Center: Request more information

                                Midwestern Regional Medical Center: Request more information

                               Southeastern Regional Medical Center: Request more information

This trial is offered at the following facilities: Western Regional Medical Center,Eastern Regional Medical Center,Midwestern Regional Medical Center,Southeastern Regional Medical Center,Southwestern Regional Medical Center

Combination Tissue Plasminogen Activator (TPA) and Dornase Alpha (DNASE) Administration through Intrapleural Catheters for the Treatment of Loculated or Non-Draning Malignant Pleural Effusions

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This trial is offered at the following facilities: Eastern Regional Medical Center

Head and neck cancer

Phase II Study of MEDI4736 Monotherapy in the Treatment of Patients With Recurrent or Metastatic SCCHN

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase Ib/II Study of Pembrolizumab and Monoclonal Antibody Chemotherapy in Patients with Advanced Cancer (PembroMab)

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This trial is offered at the following facilities: Western Regional Medical Center

Hodgkin lymphoma

Randomized, Open-label, Phase 3 Trial of A+AVD Versus ABVD as Frontline Therapy in Patients With Advanced Classical Hodgkin Lymphoma

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This trial is offered at the following facilities: Midwestern Regional Medical Center

Hodgkin's lymphoma

A Phase Ib/II Study of Pembrolizumab with Chemotherapy in Patients with Advanced Lymphoma (PembroHeme)

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This trial is offered at the following facilities: Western Regional Medical Center

Kidney cancer

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Lung cancer

Multi-center Study of Metastatic Lung Tumors Targeted by Interventional Cryoablation Evaluation (SOLSTICE)

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This trial is offered at the following facilities: Southeastern Regional Medical Center

An Open-Label, Multicenter, Single-Arm, Expanded Access Study of Alectinib For Patients with Anaplastic Lymphoma Kinase-Rearranged Non-Small Cell Lung Cancer Previously Treated with Crizontinib

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This trial is offered at the following facilities: Eastern Regional Medical Center

Randomized, Double-blind, Multicenter, Phase 3 Study Comparing Veliparib plus Carboplatin and Paclitaxel versus Placebo plus Carboplatin and Paclitaxel in Previously Untreated Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

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This trial is offered at the following facilities: Midwestern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

     Request more information

This trial is offered at the following facilities: Western Regional Medical Center

Lymphoma

A Phase 3b Randomized Study of Lenalidomide (CC-5013) Plus Rituximab Maintenance Therapy Followed by Lenalidomide Single-Agent Maintenance Versus Rituximab Maintenance in Subjects with Relapsed/Refractory Follicular, Marginal Zone or Mantle Cell Lymphoma

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase Ib/II Study of Pembrolizumab with Chemotherapy in Patients with Advanced Lymphoma (PembroHeme)

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This trial is offered at the following facilities: Western Regional Medical Center

Non-Hodgkin lymphoma (NHL)

Oncoquest-L Vaccine in Patients With Previously Untreated Stage III or IV, Asymptomatic, Non-bulky Follicular Lymphoma

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This trial is offered at the following facilities: Midwestern Regional Medical Center

Non-Hodgkin's lymphoma

A Phase Ib/II Study of Pembrolizumab with Chemotherapy in Patients with Advanced Lymphoma (PembroHeme)

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This trial is offered at the following facilities: Western Regional Medical Center

Non-small cell lung cancer (NSCLC)

A Global Study to Assess the Effects of MEDI4736 in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer (ATLANTIC)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

View the trial      Request more information

This trial is offered at the following facilities: Western Regional Medical Center

A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas

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This trial is offered at the following facilities: Western Regional Medical Center

AN OPEN LABEL, MULTICENTER, PHASE 2 STUDY TO DETERMINE THE SAFETY AND EFFICACY OF BIND-014 (DOCETAXEL NANOPARTICLES FOR INJECTABLE SUSPENSION) AS A SECOND-LINE THERAPY FOR PATIENTS WITH KRAS MUTATION POSITIVE OR SQUAMOUS CELL NON-SMALL CELL LUNG CANCER

View the trial          Western Regional Medical Center: Request more information

                               Southeastern Regional Medical Center: Request more information

This trial is offered at the following facilities: Southeastern Regional Medical Center,Western Regional Medical Center

A Phase III, Randomized, Double-blind, Placebo-controlled, Multi-centre, International Study of MEDI4736 as Sequential Therapy in Patients with Locally Advanced, Unresectable Non-Small Cell Lung Cancer (Stage III) Who Have Not Progressed Following Definitive, Platinum-based, Concurrent Chemoradiation Therapy (PACIFIC)

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This trial is offered at the following facilities: Western Regional Medical Center

A safety trial of nivolumab (BMS-936558) in subjects with advanced or metastatic non-small cell lung cancer who have progressed during or after receiving at least one prior systemic regimen

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This trial is offered at the following facilities: Western Regional Medical Center,Southeastern Regional Medical Center

Ovarian cancer

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Platinum-Gemcitabine-Avastin (PGA) for Platinum-resistant/refractory, Paclitaxel-Pretreated Recurrent Ovarian and Peritoneal Carcinoma

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This trial is offered at the following facilities: Western Regional Medical Center

Pancreatic cancer

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

A Phase I/II, Two-Part, Multicenter Study to Evaluate the Safety and Efficacy of M402 in Combination with nab-Paclitaxel and Gemcitabine in Patients with Metastatic Pancreatic Cancer

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This trial is offered at the following facilities: Southeastern Regional Medical Center

A Phase Ib/II Study of Nivolumab Plus chemotherapy in Patients with Advanced cancer (NivoPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

A Randomized, Double-Blind, Phase 3 Study of the JAK1/2 Inhibitor, Ruxolitinib or Placebo in Combination With Capecitabine in Subjects With Advanced or Metastatic Adenocarcinoma of the Pancreas Who Have Failed or Are Intolerant to First-Line Chemotherapy (The JANUS 1 Study)

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This trial is offered at the following facilities: Southeastern Regional Medical Center

Pelvic cancer

Evaluation of Hyperthermia and Radiotherapy for the Treatment of Patients with Locally Advanced Tumors of the Pelvis.

This trial is offered at the following facilities: Southwestern Regional Medical Center,Eastern Regional Medical Center

Small cell lung cancer (SCLC)

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

Soft tissue sarcoma

A Phase Ib/II Study of Pembrolizumab Plus Chemotherapy in Patients with Advanced Cancer (PembroPlus)

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This trial is offered at the following facilities: Western Regional Medical Center

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