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Cancer Treatment Centers of America

Total marrow irradiation (TMI)

We may use total marrow irradiation (TMI) for patients undergoing stem cell transplantation for the treatment of blood and bone marrow cancers, such as leukemia, lymphoma and multiple myeloma.

TMI, a form of total body irradiation (TBI), is designed to allow a more precisely-focused radiation to the major marrow sites where the cancer cells may reside. Marrow is the soft, sponge-like tissue found inside most bones.

Using TomoTherapy®, TMI targets the radiation dosage to the skeletal bone structure, helping to improve recovery time and reduce radiation exposure to healthy organs.

When used before a stem cell transplant, TMI can help the body make room for new, healthy bone marrow cells and may help prevent the body’s rejection of the donated stem cells.

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