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Cancer Treatment Centers of America

Intra-arterial chemotherapy for liver cancer

IAC for liver cancer

With intra-arterial chemotherapy (IAC), the tumor in the liver receives the chemotherapy drug, Most of which is broken down by the liver before it can reach the rest of the body. As a result, IAC may cause fewer side effects than traditional chemotherapy treatment.

What is intra-arterial chemotherapy?

Intra-arterial chemotherapy (IAC) delivers chemotherapy drugs directly to a tumor, while reducing exposure to healthy tissues. This delivery method also reduces side effects, like nausea and vomiting, and enhances the cancer-killing properties of the drugs.

How it works

During IAC, a thin catheter is threaded through the femoral artery in the right leg. Using image guidance, chemotherapy is injected directly into the hepatic artery, which is the main blood vessel that delivers blood to the liver.

IAC allows high doses of chemotherapy drugs to be targeted directly to the cancerous tissue for a longer period of time, without exposing the entire body to the effect of the drugs.

This method of chemotherapy is primarily used for the treatment of liver cancer, but may also be used for the treatment of cancers that have spread to the liver.

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