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Cancer Treatment Centers of America

Calypso® 4D Localization System™ for liver cancer

Calypso® 4D Localization System™ for liver cancer

The liver can move during radiation treatment as a result of breathing and normal movement in the intestines. Typically, radiation oncologists expand the treatment area to ensure the moving target is irradiated. In the process, larger amounts of healthy tissue in or near the liver may also be affected, leading to a high risk of liver damage, stomach ulcer or other side effects.

In this recent generation of the Calypso system, the Beacons are able to show the position of the patient’s tumor 25 times a second, and automatically shut the beam off in the event of a cough, sneeze, stomach bubble or other internal change of position that moves the tumor out of the X-ray beam. By targeting cancer cells and avoiding nearby healthy tissues, Calypso spares the bladder, colon and other critical structures. Common side effects of liver cancer radiation therapy, such as risk of liver damage, may be reduced through the use of Calypso technology.

What is the Calypso® 4D Localization System™?

The Calypso® 4D Localization System™ helps our doctors deliver focused doses of radiation with greater precision to liver cancer patients receiving external beam radiation therapy (EBRT).

Also known as GPS for the Body®, this technology allows our liver cancer radiation therapy team to continuously track movement of the liver in real time and concentrate radiation to the tumor.

The Calypso system features a 4D Console™ that allows our radiation oncologists to see exactly where the tumor is during radiation treatment. Before treatment, patients undergo a simple outpatient procedure, where Beacon® transponders are implanted into the skin using ultrasound guidance. Each transponder is as small as a grain of rice. The Beacon transponders then communicate with Calypso during radiation treatment using safe, radiofrequency waves.

Calypso is currently FDA approved for use in the treatment of liver cancer, as well as all soft-tissue tumors, except those in the lung.