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Cancer Treatment Centers of America

Lab tests for breast cancer

Lab tests: Tumor tests & genetic tests for breast cancer

  • Genomic tumor assessment: Genomic testing examines a tumor on a genetic level to find the DNA alterations that are driving the growth of cancer. By identifying the mutations that occur in a cancer cell's genome, we can better understand what caused the tumor and tailor treatment based on these findings. Learn more about genomic tumor assessment.
  • Oncotype DX® : The Oncotype DX test (also called the 21-gene test) is used to determine if chemotherapy is likely to benefit women with early stage breast cancer. This lab test also helps us to know the likelihood of disease recurrence. With this information, you and your doctor can make more informed decisions about your breast cancer treatment.
  • Mammaprint+Blueprint®: The Mammaprint® and Blueprint® genomic lab tests are used to decode a breast tumor's unique traits so we can craft a targeted treatment plan specific to each patient’s individual needs. Mammaprint can be used to determine the risk that a patient’s cancer will return. Blueprint can be used to determine which of the tumor’s mutations are dictating the cancer’s behavior. When used with the Mammaprint assay, Blueprint can narrowly define each tumor into a subtype classification, affording us a clearer picture for a more precise treatment strategy.
  • Tumor molecular profiling: For this lab test, we remove a sample of the primary tumor, metastatic tumor or recurrent breast tumor, often as part of a biopsy or other surgery. Then, we test for a variety of enzymes, proteins and genes to identify which drug therapies are likely to be most effective. Examples of tests include HER2 tumor tests and hormone receptor tests. Learn more about tumor molecular profiling.

What is a CBC (complete blood count)?

A complete blood count (CBC) is a common laboratory test used to measure blood counts (or the number of blood cells circulating in the bloodstream). A CBC measures the level of red blood cells (which carry oxygen throughout the body), white blood cells (which fight infection), and platelets (which help with blood clotting) in a blood sample. A CBC also measures hemoglobin (a protein in red blood cells that carries oxygen) and hematocrit (the ratio of red blood cells to plasma).