Dr. Sybilann Williams: Intraperitoneal chemotherapy is chemotherapy that is directed, directly to the abdominal cavity. The certain types of gynecological cancers such as ovarian cancer can spread within the abdominal cavity its self. Primary peritoneal carcinoma can also do that, and basically intraperitoneal chemotherapy involves instilling a solution of chemotherapy drugs directly into the area that’s at risk. The advantage to it is that the cancer cells themselves bathed in a solution of the chemotherapy it doesn’t have to get there through the blood stream. And there is a significant increase in the concentration of chemotherapy drug that the patients, actually, well that the cancer cells are exposed to.