Cancer Treatment Centers of America

Colony stimulating factors

Substances that assist the bone marrow in producing blood cells. Colony stimulating factors (CSF) are growth factors naturally produced in the body. Some forms of colony-stimulating factors include filigrastim (also called granulocyte colony-stimulating factor and G-CSF), sargramostim (also called granulocyte-macrophage colony-stimulating factor and GM-CSF) and promegapoietin.

Because some cancer treatments (e.g., chemotherapy) can affect white blood cells (which help fight infection), colony-stimulating factors may be introduced to help support white blood cell levels and strengthen the immune system. Colony-stimulating factors may also be used following a bone marrow transplant to help the new marrow start producing white blood cells.

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