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Soft Tissue Sarcoma Hyperthermic Intraperitoneal Chemotherapy

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Hyperthermic Intraperitoneal Chemotherapy for Soft Tissue Sarcoma 

For soft tissue sarcomas that are located in the abdomen or uterus, such as liposarcomas and pleomorphic undifferentiated sarcomas, hyperthermic intraperitoneal chemotherapy (HIPEC) may be a chemotherapy treatment option for you.

One of the most innovative chemotherapy treatment methods available, HIPEC is a heated, sterilized chemotherapy solution that is delivered directly to the abdomen during a surgical procedure.

First, a surgical oncologist will perform surgery to remove the visible soft tissue sarcoma tumor within the abdomen. Then, using sophisticated technology and tools, the surgical oncologist administers the heated chemotherapy solution to penetrate and destroy microscopic cancer cells that remain in the abdomen after surgery.

Advantages of HIPEC Treatment for Soft Tissue Sarcoma

  • Hyperthermic intraperitoneal chemotherapy allows for higher doses of chemotherapy than are usually possible with traditional chemotherapy delivery.
  • Heating the chemotherapy drugs (hyperthermia) improves absorption by tumors and makes the cancer cells more susceptible to this form of chemotherapy treatment. 
  • The chemotherapy is confined within the abdomen, minimizing exposure to the rest of the body. This can reduce some of the side effects that may come from chemotherapy, such as nausea, fatigue and vomiting.

Although gastrointestinal stromal tumors (GISTs) occur in the digestive system, these tumors do not respond well to standard chemotherapy. Patients with GISTs are not likely to benefit from soft tissue sarcoma HIPEC treatment.

Next Topic: Soft Tissue Sarcoma Chemoembolization

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