Cancer Treatment Centers of America
(800) 615-3055

Have questions? Call (800) 615-3055 to speak to a cancer information specialist.

Non-Hodgkin lymphoma stages

Making an educated treatment decision begins with the stage, or progression, of the disease. The grade and stage of non-Hodgkin lymphoma are important factors in evaluating treatment options.

Our cancer doctors use a variety of diagnostic tests to evaluate non-Hodgkin lymphoma and develop an individualized treatment plan.

Recurrent non-Hodgkin lymphoma

Non-Hodgkin lymphoma (NHL) is a malignant adult cancer that develops in the lymph system. The disease becomes metastatic when it spreads from where it first developed and invades other areas of the body. The human body has more than 500 lymph nodes that form the immune system. Clusters of lymph nodes can be found in the neck, armpits, groin, abdomen, pelvis and chest. Non-Hodgkin lymphoma (NHL) may develop in any area of body where lymph nodes are found.

Recurrent lymphoma occurs when the cancer has come back after treatment. It may relapse in the area where it first developed or return in another part of the body. Recurrence may occur at any time, shortly after treatment has ended or years later. This is called relapsed non-Hodgkin lymphoma.

NHL may be found in different organs, so symptoms of recurrent non-Hodgkin lymphoma vary. NHL symptoms may be non-specific or mimic the symptoms common to other illnesses, such as the cold or flu. But unlike the cold and flu, non-Hodgkin lymphoma symptoms typically do not go away. If you have symptoms that grow in intensity or persist for more than two weeks, you should see your doctor.

Symptoms of recurrent cancer vary from person to person. Some common recurrent non-Hodgkin lymphoma signs and symptoms include:

  • Unexplained fever
  • Swelling in the lymph nodes in the neck, underarms or groin
  • Night sweats (often soaking the sheets) and/or chills
  • Persistent fatigue, lethargy or feelings of tiredness
  • Loss of appetite, nausea or vomiting
  • Unexplained weight loss
  • Abdominal pain or swelling or feeling full
  • Skin rash or itchy skin (pruritus)
  • Coughing, shortness of breath or chest pain

Follow-up appointments with your oncologist are important in detecting cancer relapse early. Most recurrences of aggressive NHL occur within two years of treatment. Cancer recurrence rates for NHL vary widely, depending on the lymphoma type and stage, the patient’s age and other variables.

We're here to guide you through the cancer journey

We understand you may be feeling overwhelmed with questions and concerns about your type of cancer and what it all means. We're here to help guide you through the process.

Our hospital
Explore our cancer hospitals, which house the latest treatments, technologies and integrative oncology services under one roof.
Patient centered
Discover our patient-centered approach, and how you get all your questions answered in a single visit by a dedicated team of cancer experts.
Contact us
Discuss treatment options with an Oncology Information Specialist, who is available 24/7 at (800) 615-3055, or chat with us.

An accurate cancer diagnosis

accurate cancer diagnosis

Our team of cancer experts uses advanced, minimally invasive diagnostic technology to detect cancerous cells anywhere in the body.