Calypso® 4D Localization System™
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Calypso® 4D Localization System™
Dr. Bernard Eden describes the benefits of the Calypso® 4D Localization System™. Hear how this innovative technology monitors the motion of the prostate gland during radiation treatment to accurately locate and target prostate cancer cells.
The Calypso® 4D Localization System™ helps our doctors deliver focused doses of radiation with greater accuracy to prostate cancer patients receiving external beam radiation therapy .
The prostate can move during radiation treatment as a result of breathing and normal movement in the intestines. Typically, radiation oncologists expand the treatment area to ensure the moving target is irradiated. In the process, healthy tissue near the prostate may also be affected, leading to a high rate of urinary, bowel and sexual side effects.
Also known as GPS for the Body®, this technology allows our radiation therapy team to continuously track movement of the prostate in real time and concentrate radiation to the tumor. By targeting cancer cells and avoiding nearby healthy tissues, Calypso spares the bladder, colon and other critical structures. Common side effects of radiation treatment for prostate cancer patients, such as incontinence and erectile dysfunction, may be greatly minimized.
The Calypso system features a 4D Console™ that allows our radiation oncologists to see exactly where the tumor is during radiation treatment. Before treatment, patients undergo a simple outpatient procedure. Three Beacon® transponders are implanted into the prostate through the rectum, using ultrasound guidance. Each transponder is as small as a grain of rice. The Beacon transponders then communicate with Calypso during radiation treatment using safe, radiofrequency waves.
Calypso is currently FDA approved for use in the treatment of prostate cancer. This promising technology may eventually be used in the treatment of other cancers, including breast and lung cancers.
Radiation Therapy
- 3D Conformal Radiation
- Accelerated Partial Breast Irradiation (APBI)
- BrainLAB SRS
- Calypso® 4D Localization System™
- Contura™
- Cyberknife (see Stereotactic Radiosurgery)
- Deep Tissue Hyperthermia
- External Beam Radiation Therapy (EBRT)
- Gamma Knife (see Stereotactic Radiosurgery)
- High-Dose Rate (HDR) Brachytherapy
- Hyperthermia (also see Local Hyperthermia, Deep Tissue Hyperthermia)
- Intensity Modulated Radiation Therapy (IMRT)
- Image Guided Radiation Therapy (IGRT)
- Intraoperative Radiation Therapy (IORT)
- LightSpeed RT
- Local Hyperthermia
- MammoSite® RTS
- Radioactive Protectants
- Rapid Arc™
- Respiratory Gating
- Radioiodine Ablation (see Systemic Radiation Therapy)
- Stereotactic Radiosurgery (SRS)
- Stereotactic Body Radiation Therapy (SBRT)
- Systemic Radiation Therapy
- TheraSphere®
- TomoTherapy® HI-ART
- Total Body Irradiation (TBI)
- Total Marrow Irradiation (TMI)
- Trilogy™



