Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
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Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a heated, sterilized chemotherapy solution which is delivered directly to the abdomen during a surgical procedure. First, surgical oncologists perform surgery to remove visible tumors within the abdomen. Then, using sophisticated technology and tools, the surgical oncologists administer the chemotherapy solution to penetrate and destroy cancer cells that remain in the abdomen after surgery.
HIPEC is a treatment option for people who have advanced surface spread of cancer within the abdomen, without disease involvement outside of the abdomen. It may be used to treat some cases of:
- Colorectal cancer
- Appendiceal cancer
- Ovarian cancer
- Stomach cancer
- Primary peritoneal cancer
In comparison to traditional chemotherapy delivery, HIPEC allows for higher doses of chemotherapy treatment. Heating the solution (i.e., hyperthermia) also enhances the power of the chemotherapy, improving absorption by tumors and susceptibility of cancer cells to chemotherapy. Furthermore, because the chemotherapy is kept within the abdomen, it minimizes the rest of the body’s exposure to the treatment. This helps reduce some chemotherapy side effects.
Chemotherapy
- Chemoembolization
- Chemotherapy Resistance Testing (see Tumor Molecular Profiling)
- Chronotherapy
- Extreme Drug Resistance (see Tumor Molecular Profiling)
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Intra-Arterial Chemotherapy (IAC)
- Intraperitoneal Chemotherapy
- Intrathecal Chemotherapy
- Intratumoral Chemotherapy
