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Cabazitaxel (Jevtana®)

Cabazitaxel

Brand Name: Jevtana®

Cabazitaxel is used in the treatment of prostate cancer.

Cabazitaxel is in a class of drugs called microtubule inhibitors. It works by interfering with the process of cell division, thereby slowing or stopping the spread of cancer.

This medication is given as an injection into a vein (intravenous). Each injection takes about one hour. Usually, cabazitaxel is given once every three weeks. Prednisone is also given at the same time as cabazitaxel, and must be taken exactly as prescribed. The exact dose and schedule of cabazitaxel plus prednisone depends on how well the cancer is responding to the drug and several other factors. Your doctor will determine the approach that is best for you.

Cabazitaxel side effects

To prevent problematic interactions between cabazitaxel and other drugs, be sure to tell your doctor if you are allergic to any medications, and what other medications and supplements you are currently taking. You should also inform your doctor if you have or ever had liver tumor, liver disease, or kidney disease. Cabazitaxel is used only in men with prostate cancer.

Possible side effects of cabazitaxel may include:

  • Nausea
  • Heartburn
  • Constipation
  • Stomach pain
  • Change in sense of taste
  • Loss of appetite
  • Weight loss
  • Swelling of the inside of the mouth
  • Headache
  • Joint or back pain
  • Numbness, burning, or tingling in the hands, feet, arms, or legs
  • Hair loss

Some of cabazitaxel’s side effects can be serious. Call your doctor immediately if you experience any of these symptoms:

  • Diarrhea
  • Vomiting
  • Swelling of the face, arms, hands, feet, ankles, or lower legs
  • Decreased urination
  • Blood in the urine
  • Irregular heartbeat
  • Dry mouth, decreased sweating, dark urine, or other signs of dehydration
  • Shortness of breath
  • Pale skin
  • Unusual bruising or bleeding
  • Tiredness or weakness

Please note that this is not a comprehensive list. Patients may experience additional effects not mentioned above.

At Cancer Treatment Centers of America (CTCA), your team of cancer experts will explain each of the side effects of cabazitaxel with you in detail, as well as the side effects and expectations of all other medications planned as part of your individualized treatment plan.

Cabazitaxel for cancer treatment

Cabazitaxel is approved by the FDA for the following:

  • In combination with prednisone for the treatment of prostate cancer that has already been treated with other medications

At Cancer Treatment Centers of America (CTCA), our integrative approach to cancer treatment works to fight your disease on all fronts and ensures that you remain at the center of everything we do. We encourage participation from both you and your family to make certain you are comfortable with all decisions made regarding your treatment.

The information provided here is for educational purposes only. In no way should it be considered as offering medical advice. Cancer Treatment Centers of America assumes no responsibility for how this material is used. Please check with a physician if you suspect you are ill. Also note that while Cancer Treatment Centers of America frequently updates its contents, medical information changes rapidly. Therefore, some information may be out of date.

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