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Charles Komen Brown

charles brown

Medical Director of Surgery, Midwestern Regional Medical Center


Surgical Oncology

Education and Postdoctoral Training


Bachelor of Science, Interdisciplinary Studies in Biological Medicines, University of Florida College of Liberal Arts and Sciences, Gainesville

Medical School

University of Florida College of Medicine, Gainesville PhD in Virology, University of Florida College of Medicine, Gainesville


General Surgery, University of Arizona Affiliated Hospital, Tucson Chief Resident, General Surgery University of Arizona Affiliated Hospital, Tucson


Research Fellow & Clinical Associate, Oncology Surgery Branch, National Cancer Institute, National Institute of Health, Bethesda, Maryland Biological Therapy for Cancer, University of Pittsburgh Medical Center Surgical Oncology, University of Chicago Hospitals

Academic Honors & Awards

  • Federal Executive Board Excellence in Government Award for Research
  • Robert Baker Teaching Award, Department of Surgery, University of Chicago
  • Charles E. Huggins Research Award, Department of Surgery, University of Chicago
  • Society of Surgical Oncology, James Ewing Oncology Fellowship in Basic Research Award
  • Walt Oppelt Memorial Award for Excellence in Pharmacology and Therapeutics, University of Florida, College of Medicine
  • American Federation for Clinical Research, Medical Student Award
  • Phi Beta Kappa National Honor Society
  • Phi Kappa Phi National Honor Society
  • Golden Key National Honor Society
  • Alpha Epsilon Delta, Premedical Honor Society
  • University of Florida Outstanding Scholarship Award
  • United States National Leadership Merit Awards
  • Named a Top Doctor in US News & World Report
  • Named a Top Doctor by Castle Connolly
  • Twice named in “America’s Top Doctors” (11th and 12th editions)
  • Twice named in “America’s Top Doctors for Cancer” (7th and 8th editions)
  • Named Top Doctor – Surgery by Chicago Magazine (2012)


  • American Board of Surgery
  • National Board of Medical Examiners

Clinical Research

Eight years of clinical research in the following areas: Tumor Angiogenesis. Molecular Targeting of Tumors, Cancer Prevention. Regional Therapy of Cancer and Biologic Therapy for Cancer

Previous Positions

  • Assistant Professor of Surgery, University of Pittsburgh, Department of Surgery, Division of Surgical Oncology, Pittsburgh
  • Attending Surgeon, Pittsburgh VA Health Care Systems, University Drive Division, Department of Surgery, Pittsburgh
  • Faculty, David C. Koch Regional Perfusion, Cancer Therapy Center, Pittsburgh

Professional Organizations/Membership

  • Member, American Society of Clinical Oncology
  • Member, Society of Surgical Oncology
  • Associate Member, American Association for Cancer Research
  • Member, American College of Surgeons
  • Member, American Medical Association
  • Past Member Career Development Committee; Fellows Liaison; Publication Committee, American Society of Clinical Oncology
  • Past Member, Eastern Cooperative Oncology Group
  • Past Member, University of Pittsburgh Cancer Institute, Protocol Review Committee
  • Past Member, Veteran Administration Pittsburgh Medical Center, Cancer Committee
  • Past Member, Commissioned Officer Association of the USPHS
  • Past Vice President, American Medical Student Association Florida Chapter
  • Past Committee Chairman, University of Florida Medical College Council


Multicenter, Phase II Study of Axitinib, a Selective Second-generation Inhibitor of Vascular Endothelial Growth Factor Receptors 1, 2, and 3, in Patients with Metastatic Melanoma

Phase I Study of Hyperthermic Isolated Hepatic Perfusion with Oxaliplatin in the Treatment of Unresectable Liver Metastases from Colorectal Cancer

Glioblastoma Cells Block Radiation-mediated Programmed Cell Death of Endothelial Cells

Primary author or co-author of abstracts, articles and publications, including:

Brown C.K., Kirkwood J.M. Medical Management of melanoma. Surgical Clinics of North America 83(2):283-322, viii, 2003.

Brown, C.K., Kirkwood, J.M.: Immunotherapy of cancer. Horizons in Cancer Therapeutics 2(1): 3-25, 2001.

Brown, C.K.: Melanoma, In Brown, Rini, and Connell (eds) Manual of Cancer Medicine, Brian Decker Publishers, Inc., Hamilton, Canada, 2005.

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